https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Antimicin
Antimicin - Revision history
2026-04-07T01:49:23Z
Revision history for this page on the wiki
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https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7838&oldid=prev
MDolinar: /* Viri */
2013-02-04T12:06:32Z
<p><span dir="auto"><span class="autocomment">Viri</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:06, 4 February 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">* [http://books.google.si/books?id=D1ko_DTobrIC&printsec=frontcover&dq=-%09D.+Hames,+AND.+Hooper:+Biochemistry:+Third+edition&hl=sl&sa=X&ei=aibnUKbzBaKI4gSWkIDQAQ&redir_esc=y#v=onepage&q=-%09D.%20Hames%2C%20AND.%20Hooper%3A%20Biochemistry%3A%20Third%20edition&f=false D. Hames, N. Hooper: Biochemistry: Third edition, School of Biochemistry and Microbiology, University of Leeds, Leeds, UK, 2005, stran 379]</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* P. Karlson: Biokemija: 10. izdaja, državna založba Slovenije, Ljubljana, Slovenija, 1980, stran 191</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* P. Karlson: Biokemija: 10. izdaja, državna založba Slovenije, Ljubljana, Slovenija, 1980, stran 191</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Bycroft, Barrie W.: Dictionary of antibiotics and related substances: New York : Chapman and Hall; London, 1988, stran 128</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Bycroft, Barrie W.: Dictionary of antibiotics and related substances: New York : Chapman and Hall; London, 1988, stran 128</div></td></tr>
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MDolinar
https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7633&oldid=prev
Tilen Simšič: /* Antimicin */
2013-01-04T19:42:06Z
<p><span dir="auto"><span class="autocomment">Antimicin</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:42, 4 January 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 (slika)] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu ''Streptomyces'' in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 (slika)] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 (slika)] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu ''Streptomyces'' in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 (slika)] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C<sub>28</sub>H<sub>40</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično in protivirusno sredstvo), antimicin A2 (<del style="font-weight: bold; text-decoration: none;">Cˇ27Hˇ38Nˇ2Oˇ9 </del>-> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (C<sub>25</sub>H<sub>34</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično srdestvo), '''antimicin A5''' (C<sub>24</sub>H<sub>32</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično sredstvo) in '''antimicin A6''' (C<sub>23</sub>H<sub>30</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [[blastomicin]] (C<sub>26</sub>H<sub>36</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije ''S. blastmyceticus'') in [[deisovalerilblastomicin]] (C<sub>21</sub>H<sub>28</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično sredstvo).</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C<sub>28</sub>H<sub>40</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično in protivirusno sredstvo), antimicin A2 (<ins style="font-weight: bold; text-decoration: none;">C<sub>27</sub>H<sub>38</sub>N<sub>2</sub>O<sub>9</sub> </ins>-> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (C<sub>25</sub>H<sub>34</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično srdestvo), '''antimicin A5''' (C<sub>24</sub>H<sub>32</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično sredstvo) in '''antimicin A6''' (C<sub>23</sub>H<sub>30</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [[blastomicin]] (C<sub>26</sub>H<sub>36</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije ''S. blastmyceticus'') in [[deisovalerilblastomicin]] (C<sub>21</sub>H<sub>28</sub>N<sub>2</sub>O<sub>9</sub> -> protiglivično sredstvo).</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. </div></td></tr>
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Tilen Simšič
https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7632&oldid=prev
Tilen Simšič: /* Antimicin */
2013-01-04T19:40:53Z
<p><span dir="auto"><span class="autocomment">Antimicin</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 (slika)] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu ''Streptomyces'' in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 (slika)] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 (slika)] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu ''Streptomyces'' in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 (slika)] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (<del style="font-weight: bold; text-decoration: none;">C28H40N2O9 </del>-> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (<del style="font-weight: bold; text-decoration: none;">Cˇ25Hˇ34Nˇ2Oˇ9 </del>-> protiglivično srdestvo), '''antimicin A5''' (<del style="font-weight: bold; text-decoration: none;">Cˇ24Hˇ32Nˇ2Oˇ9 </del>-> protiglivično sredstvo) in '''antimicin A6''' (<del style="font-weight: bold; text-decoration: none;">Cˇ23Hˇ30Nˇ2Oˇ9 </del>-> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [[blastomicin]] (<del style="font-weight: bold; text-decoration: none;">Cˇ26Hˇ36Nˇ2Oˇ9 </del>-> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije ''S. blastmyceticus'') in [[deisovalerilblastomicin]] (<del style="font-weight: bold; text-decoration: none;">Cˇ21Hˇ28Nˇ2Oˇ9 </del>-> protiglivično sredstvo).</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (<ins style="font-weight: bold; text-decoration: none;">C<sub>28</sub>H<sub>40</sub>N<sub>2</sub>O<sub>9</sub> </ins>-> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (<ins style="font-weight: bold; text-decoration: none;">C<sub>25</sub>H<sub>34</sub>N<sub>2</sub>O<sub>9</sub> </ins>-> protiglivično srdestvo), '''antimicin A5''' (<ins style="font-weight: bold; text-decoration: none;">C<sub>24</sub>H<sub>32</sub>N<sub>2</sub>O<sub>9</sub> </ins>-> protiglivično sredstvo) in '''antimicin A6''' (<ins style="font-weight: bold; text-decoration: none;">C<sub>23</sub>H<sub>30</sub>N<sub>2</sub>O<sub>9</sub> </ins>-> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [[blastomicin]] (<ins style="font-weight: bold; text-decoration: none;">C<sub>26</sub>H<sub>36</sub>N<sub>2</sub>O<sub>9</sub> </ins>-> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije ''S. blastmyceticus'') in [[deisovalerilblastomicin]] (<ins style="font-weight: bold; text-decoration: none;">C<sub>21</sub>H<sub>28</sub>N<sub>2</sub>O<sub>9</sub> </ins>-> protiglivično sredstvo).</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. </div></td></tr>
</table>
Tilen Simšič
https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7631&oldid=prev
Tilen Simšič: /* Antimicin */
2013-01-04T19:31:20Z
<p><span dir="auto"><span class="autocomment">Antimicin</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:31, 4 January 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Antimicin==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Antimicin==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 (slika)] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu <del style="font-weight: bold; text-decoration: none;">[[</del>''Streptomyces''<del style="font-weight: bold; text-decoration: none;">]] </del>in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 (slika)] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 (slika)] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu ''Streptomyces'' in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 (slika)] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [[blastomicin]] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije <del style="font-weight: bold; text-decoration: none;">[[</del>''S. blastmyceticus''<del style="font-weight: bold; text-decoration: none;">]]</del>) in [[deisovalerilblastomicin]] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [[blastomicin]] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije ''S. blastmyceticus'') in [[deisovalerilblastomicin]] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. </div></td></tr>
</table>
Tilen Simšič
https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7630&oldid=prev
Tilen Simšič: /* Antimicin */
2013-01-04T19:29:52Z
<p><span dir="auto"><span class="autocomment">Antimicin</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:29, 4 January 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Antimicin==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Antimicin==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 (slika)] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu [[Streptomyces]] in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 (slika)] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 (slika)] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu [[<ins style="font-weight: bold; text-decoration: none;">''</ins>Streptomyces<ins style="font-weight: bold; text-decoration: none;">''</ins>]] in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 (slika)] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [blastomicin] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije [S. blastmyceticus]) in [deisovalerilblastomicin] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta <ins style="font-weight: bold; text-decoration: none;">[</ins>[blastomicin<ins style="font-weight: bold; text-decoration: none;">]</ins>] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije [<ins style="font-weight: bold; text-decoration: none;">[''</ins>S. blastmyceticus<ins style="font-weight: bold; text-decoration: none;">'']</ins>]) in <ins style="font-weight: bold; text-decoration: none;">[</ins>[deisovalerilblastomicin<ins style="font-weight: bold; text-decoration: none;">]</ins>] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. </div></td></tr>
</table>
Tilen Simšič
https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7629&oldid=prev
Tilen Simšič: /* Antimicin */
2013-01-04T19:26:45Z
<p><span dir="auto"><span class="autocomment">Antimicin</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:26, 4 January 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 slika <del style="font-weight: bold; text-decoration: none;">molekule</del>] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu [[Streptomyces]] in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 slika <del style="font-weight: bold; text-decoration: none;">molekule</del>] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 <ins style="font-weight: bold; text-decoration: none;">(</ins>slika<ins style="font-weight: bold; text-decoration: none;">)</ins>] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu [[Streptomyces]] in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [[rotenona]], [[amitala]] (izoamil etil barbiturat), [[cianida]] in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 <ins style="font-weight: bold; text-decoration: none;">(</ins>slika<ins style="font-weight: bold; text-decoration: none;">)</ins>] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [blastomicin] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije [S. blastmyceticus]) in [deisovalerilblastomicin] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [blastomicin] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije [S. blastmyceticus]) in [deisovalerilblastomicin] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).</div></td></tr>
</table>
Tilen Simšič
https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7628&oldid=prev
Tilen Simšič: /* Antimicin */
2013-01-04T19:25:06Z
<p><span dir="auto"><span class="autocomment">Antimicin</span></span></p>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>----</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 slika molekule] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu [Streptomyces] in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [rotenona], [amitala] (izoamil etil barbiturat), cianida in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 slika molekule] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 slika molekule] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu <ins style="font-weight: bold; text-decoration: none;">[</ins>[Streptomyces<ins style="font-weight: bold; text-decoration: none;">]</ins>] in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg <ins style="font-weight: bold; text-decoration: none;">[</ins>[rotenona<ins style="font-weight: bold; text-decoration: none;">]</ins>], <ins style="font-weight: bold; text-decoration: none;">[</ins>[amitala<ins style="font-weight: bold; text-decoration: none;">]</ins>] (izoamil etil barbiturat), <ins style="font-weight: bold; text-decoration: none;">[[</ins>cianida<ins style="font-weight: bold; text-decoration: none;">]] </ins>in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 slika molekule] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [blastomicin] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije [S. blastmyceticus]) in [deisovalerilblastomicin] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [blastomicin] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije [S. blastmyceticus]) in [deisovalerilblastomicin] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).</div></td></tr>
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Tilen Simšič
https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7627&oldid=prev
Tilen Simšič: /* Viri */
2013-01-04T19:21:29Z
<p><span dir="auto"><span class="autocomment">Viri</span></span></p>
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:21, 4 January 2013</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Bycroft, Barrie W.: Dictionary of antibiotics and related substances: New York : Chapman and Hall; London, 1988, stran 128</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>* Bycroft, Barrie W.: Dictionary of antibiotics and related substances: New York : Chapman and Hall; London, 1988, stran 128</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>* [http://www.angelfire.com/ak2/chemists/rod9.html Antimycin</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>* [http://www.angelfire.com/ak2/chemists/rod9.html Antimycin<ins style="font-weight: bold; text-decoration: none;">]</ins></div></td></tr>
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Tilen Simšič
https://wiki.fkkt.uni-lj.si/index.php?title=Antimicin&diff=7626&oldid=prev
Tilen Simšič: New page: ==Antimicin== ---- '''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimyci...
2013-01-04T19:19:49Z
<p>New page: ==Antimicin== ---- '''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimyci...</p>
<p><b>New page</b></p><div>==Antimicin==<br />
----<br />
'''Antimicin''' [http://www.google.si/imgres?um=1&hl=sl&sa=N&tbo=d&biw=1120&bih=600&tbm=isch&tbnid=KicgBI8m8mV2YM:&imgrefurl=http://wiki.toxbank.net/w/index.php/Antimycin_A1&docid=4uuJPhBuQ2w51M&imgurl=http://wiki.toxbank.net/w/images/c/cb/AntimycinA.png&w=300&h=300&ei=dpnZUPD-Oaj04QSnxoDYBg&zoom=1&iact=hc&vpx=4&vpy=213&dur=1072&hovh=226&hovw=226&tx=111&ty=113&sig=101024508604005758240&page=1&tbnh=150&tbnw=146&start=0&ndsp=17&ved=1t:429,r:11,s:0,i:117 slika molekule] je [http://wiki.fkkt.uni-lj.si/index.php/Antibiotiki antibiotik], ki ga proizvajajo vrste iz rodu [Streptomyces] in je eden glavnih inhibitorjev [http://en.wikipedia.org/wiki/Electron_transport_chain respiratorne verige] v mitohondrijih poleg [rotenona], [amitala] (izoamil etil barbiturat), cianida in ogljikovega monoksida. Deluje tako, da zavira tok elektronov iz citokroma b do [http://wiki.fkkt.uni-lj.si/index.php/Citokrom_c citokroma c1] [http://www.google.com/imgres?um=1&hl=sl&tbo=d&biw=960&bih=537&tbm=isch&tbnid=YlkvQVNBeYJm2M:&imgrefurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odgovor280.htm&docid=KvN2XDN1RwIp2M&imgurl=http://e-skola.biol.pmf.unizg.hr/odgovori/odg-slike/odg280-1.jpg&w=400&h=320&ei=CSnnUJPhN4qC4ASpjYGoBA&zoom=1&iact=hc&vpx=188&vpy=83&dur=5483&hovh=201&hovw=251&tx=125&ty=122&sig=103287976176703465469&page=1&tbnh=80&tbnw=95&start=0&ndsp=18&ved=1t:429,r:2,s:0,i:91 slika molekule] (del redoks sistema). Znanstveniki so odkrili, da ima toksičen efekt predvsem za sesalce in insekte pa tudi na vse ostale organizme, ki dobivajo energijo s [http://sl.wikipedia.org/wiki/Celi%C4%8Dno_dihanje celičnim dihanjem] v [http://sl.wikipedia.org/wiki/Mitohondrij mitohondrijih].<br />
<br />
Obstaja 6 tipov '''antimicinskih''' kompleksov, to so '''antimicin A1''' (C28H40N2O9 -> protiglivično in protivirusno sredstvo), antimicin A2 (Cˇ27Hˇ38Nˇ2Oˇ9 -> protiglivično sredstvo), '''antimicin A3''', '''antimicin A4''' (Cˇ25Hˇ34Nˇ2Oˇ9 -> protiglivično srdestvo), '''antimicin A5''' (Cˇ24Hˇ32Nˇ2Oˇ9 -> protiglivično sredstvo) in '''antimicin A6''' (Cˇ23Hˇ30Nˇ2Oˇ9 -> protiglivično sredstvo). V skupino '''antimicin A3''' spadata dva tipa bioloških molekul in to sta [blastomicin] (Cˇ26Hˇ36Nˇ2Oˇ9 -> protiglivično, protivirusno in protitumorsko sredstvo, ki ga proizvajajo bakterije [S. blastmyceticus]) in [deisovalerilblastomicin] (Cˇ21Hˇ28Nˇ2Oˇ9 -> protiglivično sredstvo).<br />
<br />
Antimicin je '''slabo topen v vodi''', topen je v [http://sl.wikipedia.org/wiki/Projekt:Triklormetan kloroformu] in vodni mešanici organskih topil, kot so [http://sl.wikipedia.org/wiki/Aceton aceton] idr. V alkoholnih raztopinah odlično fluorescira, zato se to lastnost uporablja za antimicinske teste. <br />
<br />
<br />
===Viri===<br />
----<br />
* [http://books.google.si/books?id=D1ko_DTobrIC&printsec=frontcover&dq=-%09D.+Hames,+AND.+Hooper:+Biochemistry:+Third+edition&hl=sl&sa=X&ei=aibnUKbzBaKI4gSWkIDQAQ&redir_esc=y#v=onepage&q=-%09D.%20Hames%2C%20AND.%20Hooper%3A%20Biochemistry%3A%20Third%20edition&f=false D. Hames, N. Hooper: Biochemistry: Third edition, School of Biochemistry and Microbiology, University of Leeds, Leeds, UK, 2005, stran 379]<br />
* P. Karlson: Biokemija: 10. izdaja, državna založba Slovenije, Ljubljana, Slovenija, 1980, stran 191<br />
* Bycroft, Barrie W.: Dictionary of antibiotics and related substances: New York : Chapman and Hall; London, 1988, stran 128<br />
* [http://www.angelfire.com/ak2/chemists/rod9.html Antimycin<br />
<br />
[[Category:LEX]]</div>
Tilen Simšič