https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Beta_oksidacija 2026-04-10T04:13:34Z Revision history for this page on the wiki MediaWiki 1.39.3 https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=6296&oldid=prev 2011-07-12T10:20:09Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:20, 12 July 2011</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>= BETA OKSIDACIJA =</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>= BETA OKSIDACIJA =</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Beta oksidacija je proces kemijskih reakcij, pri katerih se iz maščobnih kislin odcepljajo molekule acetil-CoA v obliki acil-koencima A. Te nato vstopajo v Krebsov cikel[[http://www.google.si/imgres?imgurl=http://www.mf.uni-mb.si/slike/Gradivo/Shema_krebsov_cikel.jpg&amp;imgrefurl=http://www.mf.uni-mb.si/slike/Gradivo/&amp;usg=__gHX89SZiIYkdluGMf6g2-yMY6kE=&amp;h=1754&amp;w=1240&amp;sz=215&amp;hl=sl&amp;start=0&amp;sig2=tKPHFQSTcs0myerJ5BE-LA&amp;zoom=1&amp;tbnid=bNljAiNpEMY9dM:&amp;tbnh=141&amp;tbnw=100&amp;ei=mcIETcGsHs2EswbMg_nwCQ&amp;prev=/images%3Fq%3Dkrebsov%2Bcikel%26hl%3Dsl%26sa%3DG%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=hc&amp;vpx=132&amp;vpy=42&amp;dur=13234&amp;hovh=267&amp;hovw=189&amp;tx=168&amp;ty=236&amp;oei=mcIETcGsHs2EswbMg_nwCQ&amp;esq=1&amp;page=1&amp;ndsp=15&amp;ved=1t:429,r:0,s:0]].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Beta oksidacija je proces kemijskih reakcij, pri katerih se iz maščobnih kislin odcepljajo molekule acetil-CoA v obliki acil-koencima A. Te nato vstopajo v Krebsov cikel [[http://www.google.si/imgres?imgurl=http://www.mf.uni-mb.si/slike/Gradivo/Shema_krebsov_cikel.jpg&amp;imgrefurl=http://www.mf.uni-mb.si/slike/Gradivo/&amp;usg=__gHX89SZiIYkdluGMf6g2-yMY6kE=&amp;h=1754&amp;w=1240&amp;sz=215&amp;hl=sl&amp;start=0&amp;sig2=tKPHFQSTcs0myerJ5BE-LA&amp;zoom=1&amp;tbnid=bNljAiNpEMY9dM:&amp;tbnh=141&amp;tbnw=100&amp;ei=mcIETcGsHs2EswbMg_nwCQ&amp;prev=/images%3Fq%3Dkrebsov%2Bcikel%26hl%3Dsl%26sa%3DG%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=hc&amp;vpx=132&amp;vpy=42&amp;dur=13234&amp;hovh=267&amp;hovw=189&amp;tx=168&amp;ty=236&amp;oei=mcIETcGsHs2EswbMg_nwCQ&amp;esq=1&amp;page=1&amp;ndsp=15&amp;ved=1t:429,r:0,s:0]].</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Reakcije beta oksidacije ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Reakcije beta oksidacije ==</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l7">Line 7:</td> <td colspan="2" class="diff-lineno">Line 7:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>-Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>- Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>-Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>- Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>-Oksidacija -  do ketoskupine se v prisotnosti <del style="font-weight: bold; text-decoration: none;">nikotinamida adenin dinukleotida  </del>NAD+ oksidira hidroksilna skupina.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>- Oksidacija -  do ketoskupine se v prisotnosti <ins style="font-weight: bold; text-decoration: none;">nikotinamidadenindinukleotida (</ins>NAD+<ins style="font-weight: bold; text-decoration: none;">) </ins>oksidira hidroksilna skupina.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>-Vez C-C se razcepi in sprosti se acetil CoA.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>- Vez C-C se razcepi in sprosti se acetil CoA.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>                            </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>                            </div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Acil</del>-CoA <del style="font-weight: bold; text-decoration: none;">se </del>v mitohondrijski matriks prenese kot <del style="font-weight: bold; text-decoration: none;">acil-karnitin</del>. <del style="font-weight: bold; text-decoration: none;">Maščobna kislina ima acilno skupino, ki se z acil-CoA prenese </del>na karnitin<del style="font-weight: bold; text-decoration: none;">. To reakcijo </del>katalizira karnitin-<del style="font-weight: bold; text-decoration: none;">acil-transferaza </del>I, poteka pa v medmembranskem prostoru (med notranjo in zunanjo mitohondrijsko membrano). Translokaza pomaga acilkarnitinu, da preide skozi notranjo membrano. Nazadnje se na mitohondrijski CoA v reakciji katalizirani s pomočjo karnitin-acetiltransferaze II veže acilna skupina (v mitohondrijskem matriksu).</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Acilna skupina, ki izhaja iz maščobne kisline, se preko Ac</ins>-CoA v mitohondrijski matriks prenese kot <ins style="font-weight: bold; text-decoration: none;">acilkarnitin</ins>. <ins style="font-weight: bold; text-decoration: none;">Prenos acilne skupine </ins>na karnitin <ins style="font-weight: bold; text-decoration: none;"> </ins>katalizira karnitin-<ins style="font-weight: bold; text-decoration: none;">aciltransferaza </ins>I, poteka pa v medmembranskem prostoru (med notranjo in zunanjo mitohondrijsko membrano). Translokaza pomaga acilkarnitinu, da preide skozi notranjo membrano. Nazadnje se na mitohondrijski CoA v reakciji katalizirani s pomočjo karnitin-acetiltransferaze II veže acilna skupina (v mitohondrijskem matriksu).</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Beta oksidacija maščobnih kislin z lihim številom C atomov ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Beta oksidacija maščobnih kislin z lihim številom C atomov ==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Maščobne kisline z lihim številom C atomov se razgradijo normalno z beta oksidacijo, vendar pa v zadnji cepitvi nastane propionil-CoA (fragment  s tremi C atomi). Ta se ne pretvori v acetil-CoA, <del style="font-weight: bold; text-decoration: none;">vendar </del>se v treh stopnjah pretvori v sukcinil-CoA.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Maščobne kisline z lihim številom C atomov se razgradijo normalno z beta oksidacijo, vendar pa v zadnji cepitvi nastane propionil-CoA (fragment  s tremi C atomi). Ta se ne pretvori v acetil-CoA, <ins style="font-weight: bold; text-decoration: none;">pač pa </ins>se v treh stopnjah pretvori v sukcinil-CoA.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>   </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Beta oksidacija nenasičenih maščobnih kislin ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Beta oksidacija nenasičenih maščobnih kislin ==</div></td></tr> </table>

MDolinar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4720&oldid=prev 2010-12-12T12:52:05Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:52, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l44">Line 44:</td> <td colspan="2" class="diff-lineno">Line 44:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.google.si/imgres?imgurl=http://www.mf.uni-mb.si/slike/Gradivo/Shema_krebsov_cikel.jpg&amp;imgrefurl=http://www.mf.uni-mb.si/slike/Gradivo/&amp;usg=__gHX89SZiIYkdluGMf6g2-yMY6kE=&amp;h=1754&amp;w=1240&amp;sz=215&amp;hl=sl&amp;start=0&amp;sig2=tKPHFQSTcs0myerJ5BE-LA&amp;zoom=1&amp;tbnid=bNljAiNpEMY9dM:&amp;tbnh=141&amp;tbnw=100&amp;ei=mcIETcGsHs2EswbMg_nwCQ&amp;prev=/images%3Fq%3Dkrebsov%2Bcikel%26hl%3Dsl%26sa%3DG%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=hc&amp;vpx=132&amp;vpy=42&amp;dur=13234&amp;hovh=267&amp;hovw=189&amp;tx=168&amp;ty=236&amp;oei=mcIETcGsHs2EswbMg_nwCQ&amp;esq=1&amp;page=1&amp;ndsp=15&amp;ved=1t:429,r:0,s:0</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.google.si/imgres?imgurl=http://www.mf.uni-mb.si/slike/Gradivo/Shema_krebsov_cikel.jpg&amp;imgrefurl=http://www.mf.uni-mb.si/slike/Gradivo/&amp;usg=__gHX89SZiIYkdluGMf6g2-yMY6kE=&amp;h=1754&amp;w=1240&amp;sz=215&amp;hl=sl&amp;start=0&amp;sig2=tKPHFQSTcs0myerJ5BE-LA&amp;zoom=1&amp;tbnid=bNljAiNpEMY9dM:&amp;tbnh=141&amp;tbnw=100&amp;ei=mcIETcGsHs2EswbMg_nwCQ&amp;prev=/images%3Fq%3Dkrebsov%2Bcikel%26hl%3Dsl%26sa%3DG%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=hc&amp;vpx=132&amp;vpy=42&amp;dur=13234&amp;hovh=267&amp;hovw=189&amp;tx=168&amp;ty=236&amp;oei=mcIETcGsHs2EswbMg_nwCQ&amp;esq=1&amp;page=1&amp;ndsp=15&amp;ved=1t:429,r:0,s:0</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr> </table>

Patricija Hribar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4718&oldid=prev 2010-12-12T12:45:03Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:45, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l7">Line 7:</td> <td colspan="2" class="diff-lineno">Line 7:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">-</ins>Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">-</ins>Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Oksidacija -  do ketoskupine se v prisotnosti nikotinamida adenin dinukleotida  NAD+ oksidira hidroksilna skupina.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">-</ins>Oksidacija -  do ketoskupine se v prisotnosti nikotinamida adenin dinukleotida  NAD+ oksidira hidroksilna skupina.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Vez C-C se razcepi in sprosti se acetil CoA.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">-</ins>Vez C-C se razcepi in sprosti se acetil CoA.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]</div></td></tr> </table>

Patricija Hribar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4717&oldid=prev 2010-12-12T12:44:37Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:44, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l6">Line 6:</td> <td colspan="2" class="diff-lineno">Line 6:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">- </del>Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">- </del>Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza<ins style="font-weight: bold; text-decoration: none;">.</ins></div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">- </del>Oksidacija -  do ketoskupine se v prisotnosti nikotinamida adenin dinukleotida  NAD+ oksidira hidroksilna skupina.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">- </del>Vez C-C se razcepi in sprosti se acetil CoA.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Oksidacija -  do ketoskupine se v prisotnosti nikotinamida adenin dinukleotida  NAD+ oksidira hidroksilna skupina.</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Vez C-C se razcepi in sprosti se acetil CoA.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]</div></td></tr> </table>

Patricija Hribar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4716&oldid=prev 2010-12-12T12:43:16Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:43, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l38">Line 38:</td> <td colspan="2" class="diff-lineno">Line 38:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">http://www.google.si/imgres?imgurl=http://www.mf.uni-mb.si/slike/Gradivo/Shema_krebsov_cikel.jpg&amp;imgrefurl=http://www.mf.uni-mb.si/slike/Gradivo/&amp;usg=__gHX89SZiIYkdluGMf6g2-yMY6kE=&amp;h=1754&amp;w=1240&amp;sz=215&amp;hl=sl&amp;start=0&amp;sig2=tKPHFQSTcs0myerJ5BE-LA&amp;zoom=1&amp;tbnid=bNljAiNpEMY9dM:&amp;tbnh=141&amp;tbnw=100&amp;ei=mcIETcGsHs2EswbMg_nwCQ&amp;prev=/images%3Fq%3Dkrebsov%2Bcikel%26hl%3Dsl%26sa%3DG%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=hc&amp;vpx=132&amp;vpy=42&amp;dur=13234&amp;hovh=267&amp;hovw=189&amp;tx=168&amp;ty=236&amp;oei=mcIETcGsHs2EswbMg_nwCQ&amp;esq=1&amp;page=1&amp;ndsp=15&amp;ved=1t:429,r:0,s:0</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr> </table>

Patricija Hribar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4715&oldid=prev 2010-12-12T12:42:33Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:42, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>= BETA OKSIDACIJA =</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>= BETA OKSIDACIJA =</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Beta oksidacija je proces kemijskih reakcij, pri katerih se iz maščobnih kislin v obliki acil-koencima A <del style="font-weight: bold; text-decoration: none;"> odcepljajo molekule(acetil</del>-<del style="font-weight: bold; text-decoration: none;">CoA)</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Beta oksidacija je proces kemijskih reakcij, pri katerih se iz maščobnih kislin <ins style="font-weight: bold; text-decoration: none;">odcepljajo molekule acetil-CoA </ins>v obliki acil-koencima A<ins style="font-weight: bold; text-decoration: none;">. Te nato vstopajo v Krebsov cikel[[http://www.google.si/imgres?imgurl=http://www.mf.uni-mb.si/slike/Gradivo/Shema_krebsov_cikel.jpg&amp;imgrefurl=http://www.mf.uni-mb.si/slike/Gradivo/&amp;usg=__gHX89SZiIYkdluGMf6g2-yMY6kE=&amp;h=1754&amp;w=1240&amp;sz=215&amp;hl=sl&amp;start=0&amp;sig2=tKPHFQSTcs0myerJ5BE</ins>-<ins style="font-weight: bold; text-decoration: none;">LA&amp;zoom=1&amp;tbnid=bNljAiNpEMY9dM:&amp;tbnh=141&amp;tbnw=100&amp;ei=mcIETcGsHs2EswbMg_nwCQ&amp;prev=/images%3Fq%3Dkrebsov%2Bcikel%26hl%3Dsl%26sa%3DG%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=hc&amp;vpx=132&amp;vpy=42&amp;dur=13234&amp;hovh=267&amp;hovw=189&amp;tx=168&amp;ty=236&amp;oei=mcIETcGsHs2EswbMg_nwCQ&amp;esq=1&amp;page=1&amp;ndsp=15&amp;ved=1t:429,r:0,s:0]]</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Reakcije beta oksidacije ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Reakcije beta oksidacije ==</div></td></tr> </table>

Patricija Hribar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4712&oldid=prev 2010-12-12T12:36:08Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:36, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l26">Line 26:</td> <td colspan="2" class="diff-lineno">Line 26:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://ibk.mf.uni-lj.si/teaching/biokemija2/predavanja/OksidacijaMascobnihKislinInKetonskihSpojin_VDolzan.pdf  </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://ibk.mf.uni-lj.si/teaching/biokemija2/predavanja/OksidacijaMascobnihKislinInKetonskihSpojin_VDolzan.pdf  </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.nutricionizam.com/index.php?option=com_content&amp;view=article&amp;id=433:beta-oksidacija&amp;catid=2:vani-pojmovi&amp;Itemid=25</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.nutricionizam.com/index.php?option=com_content&amp;view=article&amp;id=433:beta-oksidacija&amp;catid=2:vani-pojmovi&amp;Itemid=25</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.zbirka.si/beta-oksidacija/</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.zbirka.si/beta-oksidacija/</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html  </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html  </div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.youtube.com/watch?v=gGr4W7aZ1Uo</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.youtube.com/watch?v=gGr4W7aZ1Uo</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr> </table>

Patricija Hribar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4711&oldid=prev 2010-12-12T12:34:26Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:34, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5">Line 5:</td> <td colspan="2" class="diff-lineno">Line 5:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Reakcije beta oksidacije ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Reakcije beta oksidacije ==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116<del style="font-weight: bold; text-decoration: none;">(potek reakcij)</del>]]:</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l11">Line 11:</td> <td colspan="2" class="diff-lineno">Line 11:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Vez C-C se razcepi in sprosti se acetil CoA.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Vez C-C se razcepi in sprosti se acetil CoA.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo<del style="font-weight: bold; text-decoration: none;">(prikaz poteka reakcij)</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>                            </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>                            </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Acil-CoA se v mitohondrijski matriks prenese kot acil-karnitin. Maščobna kislina ima acilno skupino, ki se z acil-CoA prenese na karnitin. To reakcijo katalizira karnitin-acil-transferaza I, poteka pa v medmembranskem prostoru (med notranjo in zunanjo mitohondrijsko membrano). Translokaza pomaga acilkarnitinu, da preide skozi notranjo membrano. Nazadnje se na mitohondrijski CoA v reakciji katalizirani s pomočjo karnitin-acetiltransferaze II veže acilna skupina (v mitohondrijskem matriksu).</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Acil-CoA se v mitohondrijski matriks prenese kot acil-karnitin. Maščobna kislina ima acilno skupino, ki se z acil-CoA prenese na karnitin. To reakcijo katalizira karnitin-acil-transferaza I, poteka pa v medmembranskem prostoru (med notranjo in zunanjo mitohondrijsko membrano). Translokaza pomaga acilkarnitinu, da preide skozi notranjo membrano. Nazadnje se na mitohondrijski CoA v reakciji katalizirani s pomočjo karnitin-acetiltransferaze II veže acilna skupina (v mitohondrijskem matriksu).</div></td></tr> </table>

Patricija Hribar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4710&oldid=prev 2010-12-12T12:31:34Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:31, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5">Line 5:</td> <td colspan="2" class="diff-lineno">Line 5:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Reakcije beta oksidacije ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Reakcije beta oksidacije ==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116<ins style="font-weight: bold; text-decoration: none;">(potek reakcij)</ins>]]:</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov.  Nastane samo L-izomer.</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l11">Line 11:</td> <td colspan="2" class="diff-lineno">Line 11:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Vez C-C se razcepi in sprosti se acetil CoA.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>- Vez C-C se razcepi in sprosti se acetil CoA.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo<ins style="font-weight: bold; text-decoration: none;">(prikaz poteka reakcij)</ins>]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>                            </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>                            </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Acil-CoA se v mitohondrijski matriks prenese kot acil-karnitin. Maščobna kislina ima acilno skupino, ki se z acil-CoA prenese na karnitin. To reakcijo katalizira karnitin-acil-transferaza I, poteka pa v medmembranskem prostoru (med notranjo in zunanjo mitohondrijsko membrano). Translokaza pomaga acilkarnitinu, da preide skozi notranjo membrano. Nazadnje se na mitohondrijski CoA v reakciji katalizirani s pomočjo karnitin-acetiltransferaze II veže acilna skupina (v mitohondrijskem matriksu).</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Acil-CoA se v mitohondrijski matriks prenese kot acil-karnitin. Maščobna kislina ima acilno skupino, ki se z acil-CoA prenese na karnitin. To reakcijo katalizira karnitin-acil-transferaza I, poteka pa v medmembranskem prostoru (med notranjo in zunanjo mitohondrijsko membrano). Translokaza pomaga acilkarnitinu, da preide skozi notranjo membrano. Nazadnje se na mitohondrijski CoA v reakciji katalizirani s pomočjo karnitin-acetiltransferaze II veže acilna skupina (v mitohondrijskem matriksu).</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l25">Line 25:</td> <td colspan="2" class="diff-lineno">Line 25:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Viri ==  </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Viri ==  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">-</del>http://ibk.mf.uni-lj.si/teaching/biokemija2/predavanja/OksidacijaMascobnihKislinInKetonskihSpojin_VDolzan.pdf  </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>http://ibk.mf.uni-lj.si/teaching/biokemija2/predavanja/OksidacijaMascobnihKislinInKetonskihSpojin_VDolzan.pdf  </div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">-</del>http://www.nutricionizam.com/index.php?option=com_content&amp;view=article&amp;id=433:beta-oksidacija&amp;catid=2:vani-pojmovi&amp;Itemid=25</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>http://www.nutricionizam.com/index.php?option=com_content&amp;view=article&amp;id=433:beta-oksidacija&amp;catid=2:vani-pojmovi&amp;Itemid=25</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">-</del>http://www.zbirka.si/beta-oksidacija/</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>http://www.zbirka.si/beta-oksidacija/</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>-http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html  </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz</ins>-<ins style="font-weight: bold; text-decoration: none;">biologije.html </ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">http://www.youtube.com/watch?v=gGr4W7aZ1Uo</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">-http://www.youtube.com/watch?v=gGr4W7aZ1Uo</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">-http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html</del></div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr> </table>

Patricija Hribar https://wiki.fkkt.uni-lj.si/index.php?title=Beta_oksidacija&diff=4709&oldid=prev 2010-12-12T12:29:04Z

<p>New page: = BETA OKSIDACIJA = Beta oksidacija je proces kemijskih reakcij, pri katerih se iz maščobnih kislin v obliki acil-koencima A odcepljajo molekule(acetil-CoA). == Reakcije beta oksidaci...</p> <p><b>New page</b></p><div>= BETA OKSIDACIJA =<br /> <br /> Beta oksidacija je proces kemijskih reakcij, pri katerih se iz maščobnih kislin v obliki acil-koencima A odcepljajo molekule(acetil-CoA).<br /> <br /> == Reakcije beta oksidacije ==<br /> <br /> Ko nasičene maščobne kisline vstopijo v mitohondrijski matriks, se začne proces beta oksidacije. Beta oksidacija acil-CoA poteka v zaporedju štirih reakcij[[http://www.google.si/imgres?imgurl=http://www.perpetuum-lab.com.hr/bette/images/stories/beta%2520oxy%2520sign.jpg&amp;imgrefurl=http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html&amp;usg=__dm-SKHVil4XbsYEc_UasUjMD9EE=&amp;h=1670&amp;w=1272&amp;sz=269&amp;hl=sl&amp;start=15&amp;sig2=-4Kve4tNJpTzMZSHSed04Q&amp;zoom=1&amp;tbnid=OxOIFNCmK0NJ4M:&amp;tbnh=138&amp;tbnw=105&amp;ei=4r0ETebeC5G34AbH5eSpCg&amp;prev=/images%3Fq%3Dbeta%2Boksidacija%26hl%3Dsl%26biw%3D1020%26bih%3D567%26gbv%3D2%26tbs%3Disch:1&amp;itbs=1&amp;iact=rc&amp;dur=281&amp;oei=Zr0ETeCICIS1tAaFtoXlCQ&amp;esq=6&amp;page=2&amp;ndsp=18&amp;ved=1t:429,r:11,s:15&amp;tx=49&amp;ty=116]]:<br /> - Oksidacija – oksidacija enojne vezi med C-C do dvojne vezi C=C. To katalizira acil-CoA-dehidrogenaza<br /> - Hidratacija – na dvojno vez se adira voda z uvedbo OH skupine na enega od ogljikov. Nastane samo L-izomer.<br /> - Oksidacija - do ketoskupine se v prisotnosti nikotinamida adenin dinukleotida NAD+ oksidira hidroksilna skupina.<br /> - Vez C-C se razcepi in sprosti se acetil CoA.<br /> <br /> Te štiri reakcije se ponavljajo v neki spirali, zato poznamo t.i. popoln obrat spirale, ki obsega te omenjene štiri encimsko katalizirane reakcije. Pri popolnem obratu spirale pride do sprostitve acetil CoA in verige maščobne kisline, ki je po tem krajša za dva ogljikova atoma. Obrati se ponavljajo dokler se kislina ne popolnoma razgradi do acetil CoA.[[http://www.youtube.com/watch?v=gGr4W7aZ1Uo]]<br /> <br /> Acil-CoA se v mitohondrijski matriks prenese kot acil-karnitin. Maščobna kislina ima acilno skupino, ki se z acil-CoA prenese na karnitin. To reakcijo katalizira karnitin-acil-transferaza I, poteka pa v medmembranskem prostoru (med notranjo in zunanjo mitohondrijsko membrano). Translokaza pomaga acilkarnitinu, da preide skozi notranjo membrano. Nazadnje se na mitohondrijski CoA v reakciji katalizirani s pomočjo karnitin-acetiltransferaze II veže acilna skupina (v mitohondrijskem matriksu).<br /> <br /> == Beta oksidacija maščobnih kislin z lihim številom C atomov ==<br /> <br /> Maščobne kisline z lihim številom C atomov se razgradijo normalno z beta oksidacijo, vendar pa v zadnji cepitvi nastane propionil-CoA (fragment s tremi C atomi). Ta se ne pretvori v acetil-CoA, vendar se v treh stopnjah pretvori v sukcinil-CoA.<br /> <br /> == Beta oksidacija nenasičenih maščobnih kislin ==<br /> <br /> Pri standardni beta oksidaciji sodelujejo štirje encimi, vendar pa za popolno razgradnjo nenasičenih maščobnih kislin potrebujemo še dva pomožna encima. <br /> <br /> == Viri == <br /> <br /> -http://ibk.mf.uni-lj.si/teaching/biokemija2/predavanja/OksidacijaMascobnihKislinInKetonskihSpojin_VDolzan.pdf <br /> -http://www.nutricionizam.com/index.php?option=com_content&amp;view=article&amp;id=433:beta-oksidacija&amp;catid=2:vani-pojmovi&amp;Itemid=25<br /> -http://www.zbirka.si/beta-oksidacija/<br /> -http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html <br /> http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html<br /> -http://www.youtube.com/watch?v=gGr4W7aZ1Uo<br /> -http://www.perpetuum-lab.com.hr/bette/prijemni-ispiti/cesto-postavljana-pitanja-iz-biologije.html<br /> <br /> [[Category:LEX]]</div>

Patricija Hribar