https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Gelsolin 2026-06-16T12:15:40Z Revision history for this page on the wiki MediaWiki 1.45.3 https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=5333&oldid=prev 2011-02-04T10:15:47Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:15, 4 February 2011</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l11">Line 11:</td> <td colspan="2" class="diff-lineno">Line 11:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Viri==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Viri==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div># http://biologija.org/vpr/3-bice-zapiski.rtf<del style="font-weight: bold; text-decoration: none;">&amp;rct=j&amp;q=gelsolin&amp;ei=zc4DTeSxJYntsgbfq9GMCg&amp;usg=AFQjCNHTJbyiRcMDyLOllLDdrjUIwmU7GQ&amp;sig2=GgdMcuRo5u8Fjk2WH0896w&amp;cad=rja </del>(citirano 11.12.2010)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div># http://biologija.org/vpr/3-bice-zapiski.rtf(citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div># http://www.student-info.net/sis-mapa/skupina_doc/fkkt/knjiznica_datoteke/1262606693_yHn2Q9g_bio.celi_._.doc<del style="font-weight: bold; text-decoration: none;">&amp;rct=j&amp;q=gelsolin&amp;ei=8c4DTeilMc_tsgbwu4zfCQ&amp;usg=AFQjCNGPLQa_rt8nDBdvaa0fJF6Jxho7DA&amp;sig2=YyZUjPZfJufbCX5nS9lotg&amp;cad=rja (citirano 11.12.2010)</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div># http://www.student-info.net/sis-mapa/skupina_doc/fkkt/knjiznica_datoteke/1262606693_yHn2Q9g_bio.celi_._.doc(citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"># http://www.medenosrce.net/forum/forum_posts.asp?TID=1289&amp;OB=DESC&amp;PN=2 </del>(citirano 11.12.2010)</div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div># http://www.digitalna-knjiznica.bf.uni-lj.si/dn_pegan_katarina.pdf (citirano 11.12.2010)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div># http://www.digitalna-knjiznica.bf.uni-lj.si/dn_pegan_katarina.pdf (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div># http://www.yale.edu/pollard_lab/pdf/217.pdf (citirano 11.12.2010)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div># http://www.yale.edu/pollard_lab/pdf/217.pdf (citirano 11.12.2010)</div></td></tr> </table>

MDolinar https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=5332&oldid=prev 2011-02-04T10:14:21Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:14, 4 February 2011</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Gelsolin==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Gelsolin==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je aktin-vezavni protein, ki je ključni regulator za <del style="font-weight: bold; text-decoration: none;">montažo </del>in <del style="font-weight: bold; text-decoration: none;">demontažo </del>[<del style="font-weight: bold; text-decoration: none;">http://sr.wikipedia.org/sr-el/%D0%90%D0%BA%D1%82%D0%B8%D0%BD%D1%81%D0%BA%D0%B8_%D1%84%D0%B8%D0%BB%D0%B0%D0%BC%D0%B5%D0%BD%D1%82%D0%B8 </del>aktinskih filamentov].  Nahaja se v [http://sl.wikipedia.org/wiki/Citosol citosolu], [http://sl.wikipedia.org/wiki/Mitohondrij mitohondriju] ter v [http://sl.wikipedia.org/wiki/Krvna_plazma krvni plazmi].</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je aktin-vezavni protein, ki je ključni regulator za <ins style="font-weight: bold; text-decoration: none;">sestavljanje </ins>in <ins style="font-weight: bold; text-decoration: none;">razstavljanje </ins>[<ins style="font-weight: bold; text-decoration: none;">[aktin|</ins>aktinskih filamentov<ins style="font-weight: bold; text-decoration: none;">]</ins>].  Nahaja se v [http://sl.wikipedia.org/wiki/Citosol citosolu], [http://sl.wikipedia.org/wiki/Mitohondrij mitohondriju] ter v [http://sl.wikipedia.org/wiki/Krvna_plazma krvni plazmi]. <ins style="font-weight: bold; text-decoration: none;">([http://www.chem.ubc.ca/personnel/faculty/burtnick/ills/fig1.jpg slika])</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[http://<del style="font-weight: bold; text-decoration: none;">www.chem</del>.<del style="font-weight: bold; text-decoration: none;">ubc</del>.<del style="font-weight: bold; text-decoration: none;">ca</del>/<del style="font-weight: bold; text-decoration: none;">personnel</del>/<del style="font-weight: bold; text-decoration: none;">faculty/burtnick/ills/fig1</del>.<del style="font-weight: bold; text-decoration: none;">jpg Slika]</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Gelsolin je relativno velik in zapleten protein sestavljen iz 6 podenot. Vsaka izmed njih ima pet β-listov, vsakega izmed njih pa obdajata po dve </ins>[http://<ins style="font-weight: bold; text-decoration: none;">en</ins>.<ins style="font-weight: bold; text-decoration: none;">wikipedia</ins>.<ins style="font-weight: bold; text-decoration: none;">org</ins>/<ins style="font-weight: bold; text-decoration: none;">wiki</ins>/<ins style="font-weight: bold; text-decoration: none;">Alpha_helix α-vijačnici], ena pravokotno na beta-strukturo, druga pa vzporedno</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">[http://en</del>.<del style="font-weight: bold; text-decoration: none;">wikipedia</del>.<del style="font-weight: bold; text-decoration: none;">org/wiki/Gelsolin Gelsolin] je relativno velik in zapleten </del>protein <del style="font-weight: bold; text-decoration: none;">sestavljen iz 6 zelo podobnih delov. Vsak izmed njih je nato razdeljen še na pet β-listov, vsakega izmed njih pa obdajajo še po dve [http://sl.wikipedia.org/wiki/Vija%C4%8Dnica-obrat-vija%C4%8Dnica α-vijačnici], ena pravokotno na sklope, druga pa vzporedno</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Učinek proteina (pretvorba gel - tekočina oz</ins>. <ins style="font-weight: bold; text-decoration: none;">»sol«) so odkrili že leta 1947, medtem ko so protein odkrili šele leta 1979</ins>. <ins style="font-weight: bold; text-decoration: none;">Leta 1992 so </ins>protein <ins style="font-weight: bold; text-decoration: none;">prvič pripravili s pomočjo tehnologije rekombinantne DNA</ins>.  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Učinek proteina (pretvorba gel-tekočina oz. »sol«) so odkrili že leta 1947, med tem ko so protein odkrili šele leta 1979. Leta 1992 so protein prvič sintetizirali s pomočjo rekombinantne DNA tehnologije. </del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Gelsolin najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion &lt;math&gt;{Ca^{2+}}&lt;/math&gt;. Protein se zasidra med dve molekuli [<ins style="font-weight: bold; text-decoration: none;">[aktin|</ins>aktina<ins style="font-weight: bold; text-decoration: none;">]</ins>] in cepi filament na dva fragmenta. Ima pa tudi to vlogo<ins style="font-weight: bold; text-decoration: none;">, </ins>da prepreči nadaljnjo rast filamentov. Človeški <ins style="font-weight: bold; text-decoration: none;">gelsolin </ins>(hGsn) je zaviralec [<ins style="font-weight: bold; text-decoration: none;">[Celična smrt|</ins>apoptoze<ins style="font-weight: bold; text-decoration: none;">]</ins>], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic <ins style="font-weight: bold; text-decoration: none;">s </ins>poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://<ins style="font-weight: bold; text-decoration: none;">en</ins>.wikipedia.org/wiki/<ins style="font-weight: bold; text-decoration: none;">Breast_cancer </ins>rakom na dojki], vendar <ins style="font-weight: bold; text-decoration: none;">njegovega dejanskega delovanja </ins>še niso dokazali.  </div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">[http://en.wikipedia.org/wiki/</del>Gelsolin <del style="font-weight: bold; text-decoration: none;">Gelsolin] </del>najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion &lt;math&gt;{Ca^{2+}}&lt;/math&gt;. Protein se zasidra med dve molekuli [<del style="font-weight: bold; text-decoration: none;">http://en.wikipedia.org/wiki/Actin </del>aktina] in cepi filament na dva fragmenta. Ima pa tudi to vlogo da prepreči nadaljnjo rast filamentov. Človeški <del style="font-weight: bold; text-decoration: none;">[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] </del>(hGsn) je zaviralec [<del style="font-weight: bold; text-decoration: none;">http://sl.wikipedia.org/wiki/Apoptoza </del>apoptoze], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic <del style="font-weight: bold; text-decoration: none;">z </del>poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://<del style="font-weight: bold; text-decoration: none;">hr</del>.wikipedia.org/wiki/<del style="font-weight: bold; text-decoration: none;">Rak_dojke </del>rakom na dojki], vendar <del style="font-weight: bold; text-decoration: none;">njegov dejanski učinek </del>še niso dokazali.</div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Viri==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Viri==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">1.http://www.google.si/url?sa=t&amp;source=web&amp;cd=14&amp;ved=0CDcQFjADOAo&amp;url=</del>http://biologija.org/vpr/3-bice-zapiski.rtf&amp;rct=j&amp;q=gelsolin&amp;ei=zc4DTeSxJYntsgbfq9GMCg&amp;usg=AFQjCNHTJbyiRcMDyLOllLDdrjUIwmU7GQ&amp;sig2=GgdMcuRo5u8Fjk2WH0896w&amp;cad=rja (citirano 11.12.2010)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://biologija.org/vpr/3-bice-zapiski.rtf&amp;rct=j&amp;q=gelsolin&amp;ei=zc4DTeSxJYntsgbfq9GMCg&amp;usg=AFQjCNHTJbyiRcMDyLOllLDdrjUIwmU7GQ&amp;sig2=GgdMcuRo5u8Fjk2WH0896w&amp;cad=rja (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://www.student-info.net/sis-mapa/skupina_doc/fkkt/knjiznica_datoteke/1262606693_yHn2Q9g_bio.celi_._.doc&amp;rct=j&amp;q=gelsolin&amp;ei=8c4DTeilMc_tsgbwu4zfCQ&amp;usg=AFQjCNGPLQa_rt8nDBdvaa0fJF6Jxho7DA&amp;sig2=YyZUjPZfJufbCX5nS9lotg&amp;cad=rja (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">2.http://www.google.si/url?sa=t&amp;source=web&amp;cd=21&amp;ved=0CCQQFjAAOBQ&amp;url=</del>http://www.student-info.net/sis-mapa/skupina_doc/fkkt/knjiznica_datoteke/1262606693_yHn2Q9g_bio.celi_._.doc&amp;rct=j&amp;q=gelsolin&amp;ei=8c4DTeilMc_tsgbwu4zfCQ&amp;usg=AFQjCNGPLQa_rt8nDBdvaa0fJF6Jxho7DA&amp;sig2=YyZUjPZfJufbCX5nS9lotg&amp;cad=rja (citirano 11.12.2010)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://www.medenosrce.net/forum/forum_posts.asp?TID=1289&amp;OB=DESC&amp;PN=2 (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://www.digitalna-knjiznica.bf.uni-lj.si/dn_pegan_katarina.pdf (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">3.</del>http://www.medenosrce.net/forum/forum_posts.asp?TID=1289&amp;OB=DESC&amp;PN=2 (citirano 11.12.2010)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://www.yale.edu/pollard_lab/pdf/217.pdf (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://en.wikipedia.org/wiki/Gelsolin (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">4.</del>http://www.digitalna-knjiznica.bf.uni-lj.si/dn_pegan_katarina.pdf (citirano 11.12.2010)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://www.bms.ed.ac.uk/research/others/smaciver/Cyto-Topics/gelsolin_family.htm (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://www.nature.com/bjc/journal/v88/n4/abs/6600739a.html (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">5.</del>http://www.yale.edu/pollard_lab/pdf/217.pdf (citirano 11.12.2010)</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"># </ins>http://www.chem.ubc.ca/personnel/faculty/burtnick/index.shtml (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">6.</del>http://en.wikipedia.org/wiki/Gelsolin (citirano 11.12.2010)</div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">7.</del>http://www.bms.ed.ac.uk/research/others/smaciver/Cyto-Topics/gelsolin_family.htm (citirano 11.12.2010)</div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">8.</del>http://www.nature.com/bjc/journal/v88/n4/abs/6600739a.html (citirano 11.12.2010)</div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">9.</del>http://www.chem.ubc.ca/personnel/faculty/burtnick/index.shtml (citirano 11.12.2010)</div></td><td colspan="2" class="diff-side-added"></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category: LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category: LEX]]</div></td></tr> </table>

MDolinar https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=4778&oldid=prev 2010-12-12T19:37:37Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 19:37, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l2">Line 2:</td> <td colspan="2" class="diff-lineno">Line 2:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je aktin-vezavni protein, ki je ključni regulator za montažo in demontažo [http://sr.wikipedia.org/sr-el/%D0%90%D0%BA%D1%82%D0%B8%D0%BD%D1%81%D0%BA%D0%B8_%D1%84%D0%B8%D0%BB%D0%B0%D0%BC%D0%B5%D0%BD%D1%82%D0%B8 aktinskih filamentov].  Nahaja se v [http://sl.wikipedia.org/wiki/Citosol citosolu], [http://sl.wikipedia.org/wiki/Mitohondrij mitohondriju] ter v [http://sl.wikipedia.org/wiki/Krvna_plazma krvni plazmi].</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je aktin-vezavni protein, ki je ključni regulator za montažo in demontažo [http://sr.wikipedia.org/sr-el/%D0%90%D0%BA%D1%82%D0%B8%D0%BD%D1%81%D0%BA%D0%B8_%D1%84%D0%B8%D0%BB%D0%B0%D0%BC%D0%B5%D0%BD%D1%82%D0%B8 aktinskih filamentov].  Nahaja se v [http://sl.wikipedia.org/wiki/Citosol citosolu], [http://sl.wikipedia.org/wiki/Mitohondrij mitohondriju] ter v [http://sl.wikipedia.org/wiki/Krvna_plazma krvni plazmi].</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[http://www.chem.ubc.ca/personnel/faculty/burtnick/ills/fig1.jpg Slika]</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je relativno velik in zapleten protein sestavljen iz 6 zelo podobnih delov. Vsak izmed njih je nato razdeljen še na pet β-listov, vsakega izmed njih pa obdajajo še po dve [http://sl.wikipedia.org/wiki/Vija%C4%8Dnica-obrat-vija%C4%8Dnica α-vijačnici], ena pravokotno na sklope, druga pa vzporedno.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je relativno velik in zapleten protein sestavljen iz 6 zelo podobnih delov. Vsak izmed njih je nato razdeljen še na pet β-listov, vsakega izmed njih pa obdajajo še po dve [http://sl.wikipedia.org/wiki/Vija%C4%8Dnica-obrat-vija%C4%8Dnica α-vijačnici], ena pravokotno na sklope, druga pa vzporedno.</div></td></tr> </table>

Tilen Oražem https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=4662&oldid=prev 2010-12-12T00:10:07Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 00:10, 12 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l7">Line 7:</td> <td colspan="2" class="diff-lineno">Line 7:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Učinek proteina (pretvorba gel-tekočina oz. »sol«) so odkrili že leta 1947, med tem ko so protein odkrili šele leta 1979. Leta 1992 so protein prvič sintetizirali s pomočjo rekombinantne DNA tehnologije.  </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Učinek proteina (pretvorba gel-tekočina oz. »sol«) so odkrili že leta 1947, med tem ko so protein odkrili šele leta 1979. Leta 1992 so protein prvič sintetizirali s pomočjo rekombinantne DNA tehnologije.  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion <del style="font-weight: bold; text-decoration: none;">Ca2</del>+. Protein se zasidra med dve molekuli [http://en.wikipedia.org/wiki/Actin aktina] in cepi filament na dva fragmenta. Ima pa tudi to vlogo da prepreči nadaljnjo rast filamentov. Človeški [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] (hGsn) je zaviralec [http://sl.wikipedia.org/wiki/Apoptoza apoptoze], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic z poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://hr.wikipedia.org/wiki/Rak_dojke rakom na dojki], vendar njegov dejanski učinek še niso dokazali.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion <ins style="font-weight: bold; text-decoration: none;">&lt;math&gt;{Ca^{2</ins>+<ins style="font-weight: bold; text-decoration: none;">}}&lt;/math&gt;</ins>. Protein se zasidra med dve molekuli [http://en.wikipedia.org/wiki/Actin aktina] in cepi filament na dva fragmenta. Ima pa tudi to vlogo da prepreči nadaljnjo rast filamentov. Človeški [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] (hGsn) je zaviralec [http://sl.wikipedia.org/wiki/Apoptoza apoptoze], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic z poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://hr.wikipedia.org/wiki/Rak_dojke rakom na dojki], vendar njegov dejanski učinek še niso dokazali.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Viri==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Viri==</div></td></tr> </table>

Lessan15 https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=4658&oldid=prev 2010-12-11T22:19:29Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 22:19, 11 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l7">Line 7:</td> <td colspan="2" class="diff-lineno">Line 7:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Učinek proteina (pretvorba gel-tekočina oz. »sol«) so odkrili že leta 1947, med tem ko so protein odkrili šele leta 1979. Leta 1992 so protein prvič sintetizirali s pomočjo rekombinantne DNA tehnologije.  </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Učinek proteina (pretvorba gel-tekočina oz. »sol«) so odkrili že leta 1947, med tem ko so protein odkrili šele leta 1979. Leta 1992 so protein prvič sintetizirali s pomočjo rekombinantne DNA tehnologije.  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion Ca2+. Protein se zasidra med dve molekuli [http://en.wikipedia.org/wiki/Actin aktina] in cepi filament na dva fragmenta. Ima pa tudi to vlogo da prepreči nadaljnjo rast filamentov. Človeški [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] (hGsn) je zaviralec [http://sl.wikipedia.org/wiki/Apoptoza apoptoze], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic z poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://hr.wikipedia.org/wiki/Rak_dojke rakom na dojki], vendar <del style="font-weight: bold; text-decoration: none;">tega </del>še niso dokazali.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion Ca2+. Protein se zasidra med dve molekuli [http://en.wikipedia.org/wiki/Actin aktina] in cepi filament na dva fragmenta. Ima pa tudi to vlogo da prepreči nadaljnjo rast filamentov. Človeški [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] (hGsn) je zaviralec [http://sl.wikipedia.org/wiki/Apoptoza apoptoze], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic z poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://hr.wikipedia.org/wiki/Rak_dojke rakom na dojki], vendar <ins style="font-weight: bold; text-decoration: none;">njegov dejanski učinek </ins>še niso dokazali.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Viri==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Viri==</div></td></tr> </table>

Lessan15 https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=4657&oldid=prev 2010-12-11T22:18:32Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 22:18, 11 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l5">Line 5:</td> <td colspan="2" class="diff-lineno">Line 5:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je relativno velik in zapleten protein sestavljen iz 6 zelo podobnih delov. Vsak izmed njih je nato razdeljen še na pet β-listov, vsakega izmed njih pa obdajajo še po dve [http://sl.wikipedia.org/wiki/Vija%C4%8Dnica-obrat-vija%C4%8Dnica α-vijačnici], ena pravokotno na sklope, druga pa vzporedno.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je relativno velik in zapleten protein sestavljen iz 6 zelo podobnih delov. Vsak izmed njih je nato razdeljen še na pet β-listov, vsakega izmed njih pa obdajajo še po dve [http://sl.wikipedia.org/wiki/Vija%C4%8Dnica-obrat-vija%C4%8Dnica α-vijačnici], ena pravokotno na sklope, druga pa vzporedno.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Učinek proteina ( pretvorba gel-tekočina oz. »sol«) so <del style="font-weight: bold; text-decoration: none;">poznali </del>leta 1947 med tem ko so protein odkrili šele leta 1979. Leta 1992 so protein prvič sintetizirali s pomočjo rekombinantne DNA tehnologije.  </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Učinek proteina (pretvorba gel-tekočina oz. »sol«) so <ins style="font-weight: bold; text-decoration: none;">odkrili že </ins>leta 1947<ins style="font-weight: bold; text-decoration: none;">, </ins>med tem ko so protein odkrili šele leta 1979. Leta 1992 so protein prvič sintetizirali s pomočjo rekombinantne DNA tehnologije.  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion Ca2+. Protein se zasidra med dve molekuli [http://en.wikipedia.org/wiki/Actin aktina] in cepi filament na dva fragmenta. Ima pa tudi to vlogo da prepreči nadaljnjo rast filamentov. Človeški [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] (hGsn) je zaviralec [http://sl.wikipedia.org/wiki/Apoptoza apoptoze], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic z poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://hr.wikipedia.org/wiki/Rak_dojke rakom na dojki], vendar tega še niso dokazali.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://en.wikipedia.org/wiki/Gelsolin Gelsolin] najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion Ca2+. Protein se zasidra med dve molekuli [http://en.wikipedia.org/wiki/Actin aktina] in cepi filament na dva fragmenta. Ima pa tudi to vlogo da prepreči nadaljnjo rast filamentov. Človeški [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] (hGsn) je zaviralec [http://sl.wikipedia.org/wiki/Apoptoza apoptoze], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic z poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://hr.wikipedia.org/wiki/Rak_dojke rakom na dojki], vendar tega še niso dokazali.</div></td></tr> </table>

Lessan15 https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=4655&oldid=prev 2010-12-11T22:14:19Z

<p><a href="/index.php?title=User:Lessan15&amp;action=edit&amp;redlink=1" class="new" title="User:Lessan15 (page does not exist)">User:Lessan15</a> moved to <a href="/index.php?title=Gelsolin" title="Gelsolin">Gelsolin</a></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <tr class="diff-title" lang="en"> <td colspan="1" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="1" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 22:14, 11 December 2010</td> </tr><tr><td colspan="2" class="diff-notice" lang="en"><div class="mw-diff-empty">(No difference)</div> </td></tr></table>

Lessan15 https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=4654&oldid=prev 2010-12-11T22:13:12Z

<p>Gelsolin</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 22:13, 11 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l27">Line 27:</td> <td colspan="2" class="diff-lineno">Line 27:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>8.http://www.nature.com/bjc/journal/v88/n4/abs/6600739a.html (citirano 11.12.2010)</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>8.http://www.nature.com/bjc/journal/v88/n4/abs/6600739a.html (citirano 11.12.2010)</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>9.http://www.chem.ubc.ca/personnel/faculty/burtnick/index.shtml</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>9.http://www.chem.ubc.ca/personnel/faculty/burtnick/index.shtml <ins style="font-weight: bold; text-decoration: none;">(citirano 11.12.2010)</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category: LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category: LEX]]</div></td></tr> </table>

Lessan15 https://wiki.fkkt.uni-lj.si/index.php?title=Gelsolin&diff=4652&oldid=prev 2010-12-11T22:08:42Z

<p>New page: ==Gelsolin== [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je aktin-vezavni protein, ki je ključni regulator za montažo in demontažo [http://sr.wikipedia.org/sr-el/%D0%90%D0%BA%D1%8...</p> <p><b>New page</b></p><div>==Gelsolin==<br /> <br /> [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je aktin-vezavni protein, ki je ključni regulator za montažo in demontažo [http://sr.wikipedia.org/sr-el/%D0%90%D0%BA%D1%82%D0%B8%D0%BD%D1%81%D0%BA%D0%B8_%D1%84%D0%B8%D0%BB%D0%B0%D0%BC%D0%B5%D0%BD%D1%82%D0%B8 aktinskih filamentov]. Nahaja se v [http://sl.wikipedia.org/wiki/Citosol citosolu], [http://sl.wikipedia.org/wiki/Mitohondrij mitohondriju] ter v [http://sl.wikipedia.org/wiki/Krvna_plazma krvni plazmi].<br /> <br /> [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] je relativno velik in zapleten protein sestavljen iz 6 zelo podobnih delov. Vsak izmed njih je nato razdeljen še na pet β-listov, vsakega izmed njih pa obdajajo še po dve [http://sl.wikipedia.org/wiki/Vija%C4%8Dnica-obrat-vija%C4%8Dnica α-vijačnici], ena pravokotno na sklope, druga pa vzporedno.<br /> <br /> Učinek proteina ( pretvorba gel-tekočina oz. »sol«) so poznali leta 1947 med tem ko so protein odkrili šele leta 1979. Leta 1992 so protein prvič sintetizirali s pomočjo rekombinantne DNA tehnologije. <br /> <br /> [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] najdemo tako v človeških celicah (hGsh), kot tudi v živalskih, vendar neaktiviranega. Aktivira ga [http://sl.wikipedia.org/wiki/Kalcij kalcijev] ion Ca2+. Protein se zasidra med dve molekuli [http://en.wikipedia.org/wiki/Actin aktina] in cepi filament na dva fragmenta. Ima pa tudi to vlogo da prepreči nadaljnjo rast filamentov. Človeški [http://en.wikipedia.org/wiki/Gelsolin Gelsolin] (hGsn) je zaviralec [http://sl.wikipedia.org/wiki/Apoptoza apoptoze], s tem preprečuje naravno uničevanje deformiranih celic (okuženih celic, celic z poškodovano DNA, rakavih celic, odvečnih celic, ipd.). Gelsolin povezujejo z [http://hr.wikipedia.org/wiki/Rak_dojke rakom na dojki], vendar tega še niso dokazali.<br /> <br /> ==Viri==<br /> <br /> 1.http://www.google.si/url?sa=t&amp;source=web&amp;cd=14&amp;ved=0CDcQFjADOAo&amp;url=http://biologija.org/vpr/3-bice-zapiski.rtf&amp;rct=j&amp;q=gelsolin&amp;ei=zc4DTeSxJYntsgbfq9GMCg&amp;usg=AFQjCNHTJbyiRcMDyLOllLDdrjUIwmU7GQ&amp;sig2=GgdMcuRo5u8Fjk2WH0896w&amp;cad=rja (citirano 11.12.2010)<br /> <br /> 2.http://www.google.si/url?sa=t&amp;source=web&amp;cd=21&amp;ved=0CCQQFjAAOBQ&amp;url=http://www.student-info.net/sis-mapa/skupina_doc/fkkt/knjiznica_datoteke/1262606693_yHn2Q9g_bio.celi_._.doc&amp;rct=j&amp;q=gelsolin&amp;ei=8c4DTeilMc_tsgbwu4zfCQ&amp;usg=AFQjCNGPLQa_rt8nDBdvaa0fJF6Jxho7DA&amp;sig2=YyZUjPZfJufbCX5nS9lotg&amp;cad=rja (citirano 11.12.2010)<br /> <br /> 3.http://www.medenosrce.net/forum/forum_posts.asp?TID=1289&amp;OB=DESC&amp;PN=2 (citirano 11.12.2010)<br /> <br /> 4.http://www.digitalna-knjiznica.bf.uni-lj.si/dn_pegan_katarina.pdf (citirano 11.12.2010)<br /> <br /> 5.http://www.yale.edu/pollard_lab/pdf/217.pdf (citirano 11.12.2010)<br /> <br /> 6.http://en.wikipedia.org/wiki/Gelsolin (citirano 11.12.2010)<br /> <br /> 7.http://www.bms.ed.ac.uk/research/others/smaciver/Cyto-Topics/gelsolin_family.htm (citirano 11.12.2010)<br /> <br /> 8.http://www.nature.com/bjc/journal/v88/n4/abs/6600739a.html (citirano 11.12.2010)<br /> <br /> 9.http://www.chem.ubc.ca/personnel/faculty/burtnick/index.shtml<br /> <br /> [[Category: LEX]]</div>

Lessan15