https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Glukuronska_kislina 2026-04-14T05:33:18Z Revision history for this page on the wiki MediaWiki 1.39.3 https://wiki.fkkt.uni-lj.si/index.php?title=Glukuronska_kislina&diff=7821&oldid=prev 2013-02-01T11:19:28Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:19, 1 February 2013</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td> <td colspan="2" class="diff-lineno">Line 1:</td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>&#039;&#039;&#039;Glukuronska kislina&#039;&#039;&#039; je karboksilna kislina s kemijsko formulo C&lt;sub&gt;6&lt;/sub&gt;H&lt;sub&gt;10&lt;/sub&gt;O&lt;sub&gt;7&lt;/sub&gt;<del style="font-weight: bold; text-decoration: none;">. </del>[http://upload.wikimedia.org/wikipedia/commons/6/6c/Beta_D-Glucuronic_acid.svg <del style="font-weight: bold; text-decoration: none;">Slika glukuronske kisline</del>.] Njena struktura se od [[glukoza|glukoze]] razlikuje le po šestem ogljikovem atomu, ki je pri glukuronski kislini oksidiran v karboksilno kislino, pri glukozi pa je nanj vezana hidroksilna skupina.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>&#039;&#039;&#039;Glukuronska kislina&#039;&#039;&#039; je karboksilna kislina s kemijsko formulo C&lt;sub&gt;6&lt;/sub&gt;H&lt;sub&gt;10&lt;/sub&gt;O&lt;sub&gt;7&lt;/sub&gt; [http://upload.wikimedia.org/wikipedia/commons<ins style="font-weight: bold; text-decoration: none;">/thumb</ins>/6/6c/Beta_D-Glucuronic_acid.svg<ins style="font-weight: bold; text-decoration: none;">/200px-Beta_D-Glucuronic_acid.svg</ins>.<ins style="font-weight: bold; text-decoration: none;">png (formula)</ins>]<ins style="font-weight: bold; text-decoration: none;">. </ins>Njena struktura se od [[glukoza|glukoze]] razlikuje le po šestem ogljikovem atomu, ki je pri glukuronski kislini oksidiran v karboksilno kislino, pri glukozi pa je nanj vezana hidroksilna skupina.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Ločiti moramo glukuronsko in [[glukonska kislina|glukonsko]] kislino, saj obe nastaneta iz glukoze, a se pri glukonski kislini oksidira drug atom ogljika in je zato njena struktura linearna<del style="font-weight: bold; text-decoration: none;">. </del>[http://<del style="font-weight: bold; text-decoration: none;">upload</del>.<del style="font-weight: bold; text-decoration: none;">wikimedia</del>.org/<del style="font-weight: bold; text-decoration: none;">wikipedia/commons/2/2d</del>/D-Glucons%C3%A4ure_Keilstrich.svg <del style="font-weight: bold; text-decoration: none;">Slika </del>glukonske kisline.<del style="font-weight: bold; text-decoration: none;">]</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Ločiti moramo glukuronsko in [[glukonska kislina|glukonsko]] kislino, saj obe nastaneta iz glukoze, a se pri glukonski kislini oksidira drug atom ogljika in je zato njena struktura linearna [http://<ins style="font-weight: bold; text-decoration: none;">en</ins>.<ins style="font-weight: bold; text-decoration: none;">wikipedia</ins>.org/<ins style="font-weight: bold; text-decoration: none;">wiki</ins>/<ins style="font-weight: bold; text-decoration: none;">File:</ins>D-Glucons%C3%A4ure_Keilstrich.svg <ins style="font-weight: bold; text-decoration: none;">(formula </ins>glukonske kisline<ins style="font-weight: bold; text-decoration: none;">)]</ins>.</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Lastnosti==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Lastnosti==</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Molekulska formula: C&lt;sub&gt;6&lt;/sub&gt;H&lt;sub&gt;10&lt;/sub&gt;O&lt;sub&gt;7&lt;/sub&gt;</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Molekulska formula: C&lt;sub&gt;6&lt;/sub&gt;H&lt;sub&gt;10&lt;/sub&gt;O&lt;sub&gt;7&lt;/sub&gt;</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Molekulska masa: 194<del style="font-weight: bold; text-decoration: none;">.</del>14 g/mol</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Molekulska masa: 194<ins style="font-weight: bold; text-decoration: none;">,</ins>14 g/mol</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Tališče: <del style="font-weight: bold; text-decoration: none;">160°C</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Tališče: <ins style="font-weight: bold; text-decoration: none;">160 °C</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Agregatno stanje: <del style="font-weight: bold; text-decoration: none;">Trdno</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Agregatno stanje: <ins style="font-weight: bold; text-decoration: none;">trdno.</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Spojina je topna v vodi.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Spojina je topna v vodi.</div></td></tr> <tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l16">Line 16:</td> <td colspan="2" class="diff-lineno">Line 16:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Funkcije==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Funkcije==</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>V živalskih organizmih je glukuronska kislina pogosto povezana s presnovnimi procesi nekaterih snovi kot so <del style="font-weight: bold; text-decoration: none;">naprimer, </del>droge, [[bilirubin]], androgeni, [[estrogen|estrogen]], derivati maščobnih kislin. Pri presnovi teh snovi se glukuronska kislina poveže z glikozidno vezjo in s tem se poveča topnost snovi v vodi, kar pa omogoča, da se te snovi preko izločal lažje izločijo iz telesa.  </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>V živalskih organizmih je glukuronska kislina pogosto povezana s presnovnimi procesi nekaterih snovi kot so <ins style="font-weight: bold; text-decoration: none;">na primer </ins>droge, [[bilirubin]], androgeni, [[estrogen|estrogen]], derivati maščobnih kislin. Pri presnovi teh snovi se glukuronska kislina poveže z glikozidno vezjo in s tem se poveča topnost snovi v vodi, kar pa omogoča, da se te snovi preko izločal lažje izločijo iz telesa.  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Glukuronidaze==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==Glukuronidaze==</div></td></tr> </table>

MDolinar https://wiki.fkkt.uni-lj.si/index.php?title=Glukuronska_kislina&diff=7416&oldid=prev 2012-10-30T05:40:00Z

<p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 05:40, 30 October 2012</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l25">Line 25:</td> <td colspan="2" class="diff-lineno">Line 25:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Coffman B.L., King C.D., Rios G.R. and Tephly T.R. The glucuronidation of opioids, other xenobiotics, and androgens by human</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Coffman B.L., King C.D., Rios G.R. and Tephly T.R. The glucuronidation of opioids, other xenobiotics, and androgens by human</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*http://en.wikipedia.org/wiki/Glucuronic_acid</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*http://en.wikipedia.org/wiki/Glucuronic_acid</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[[Category:LEX]]</ins></div></td></tr> </table>

Tim Bencik https://wiki.fkkt.uni-lj.si/index.php?title=Glukuronska_kislina&diff=7415&oldid=prev 2012-10-29T19:23:45Z

<p>New page: &#039;&#039;&#039;Glukuronska kislina&#039;&#039;&#039; je karboksilna kislina s kemijsko formulo C&lt;sub&gt;6&lt;/sub&gt;H&lt;sub&gt;10&lt;/sub&gt;O&lt;sub&gt;7&lt;/sub&gt;. [http://upload.wikimedia.org/wikipedia/commons/6/6c/Beta_D-Glucuronic_acid.svg...</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Glukuronska kislina&#039;&#039;&#039; je karboksilna kislina s kemijsko formulo C&lt;sub&gt;6&lt;/sub&gt;H&lt;sub&gt;10&lt;/sub&gt;O&lt;sub&gt;7&lt;/sub&gt;. [http://upload.wikimedia.org/wikipedia/commons/6/6c/Beta_D-Glucuronic_acid.svg Slika glukuronske kisline.] Njena struktura se od [[glukoza|glukoze]] razlikuje le po šestem ogljikovem atomu, ki je pri glukuronski kislini oksidiran v karboksilno kislino, pri glukozi pa je nanj vezana hidroksilna skupina.<br /> <br /> Ločiti moramo glukuronsko in [[glukonska kislina|glukonsko]] kislino, saj obe nastaneta iz glukoze, a se pri glukonski kislini oksidira drug atom ogljika in je zato njena struktura linearna. [http://upload.wikimedia.org/wikipedia/commons/2/2d/D-Glucons%C3%A4ure_Keilstrich.svg Slika glukonske kisline.]<br /> ==Lastnosti==<br /> Molekulska formula: C&lt;sub&gt;6&lt;/sub&gt;H&lt;sub&gt;10&lt;/sub&gt;O&lt;sub&gt;7&lt;/sub&gt;<br /> <br /> Molekulska masa: 194.14 g/mol<br /> <br /> Tališče: 160°C<br /> <br /> Agregatno stanje: Trdno<br /> <br /> Spojina je topna v vodi.<br /> <br /> <br /> <br /> ==Funkcije==<br /> V živalskih organizmih je glukuronska kislina pogosto povezana s presnovnimi procesi nekaterih snovi kot so naprimer, droge, [[bilirubin]], androgeni, [[estrogen|estrogen]], derivati maščobnih kislin. Pri presnovi teh snovi se glukuronska kislina poveže z glikozidno vezjo in s tem se poveča topnost snovi v vodi, kar pa omogoča, da se te snovi preko izločal lažje izločijo iz telesa. <br /> <br /> ==Glukuronidaze==<br /> Glukuronidaze so encimi, ki razcepljajo glikozidno vez med glukuronsko kislino in ostalimi spojinami.<br /> <br /> ==Viri==<br /> *Mannfred A Hollinger, Introduction to Pharmacology<br /> *Coffman B.L., King C.D., Rios G.R. and Tephly T.R. The glucuronidation of opioids, other xenobiotics, and androgens by human<br /> *http://en.wikipedia.org/wiki/Glucuronic_acid</div>

Tim Bencik