https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Izolevcin
Izolevcin - Revision history
2026-04-07T00:09:38Z
Revision history for this page on the wiki
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https://wiki.fkkt.uni-lj.si/index.php?title=Izolevcin&diff=7843&oldid=prev
MDolinar at 15:06, 4 February 2013
2013-02-04T15:06:19Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 15:06, 4 February 2013</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Izolevcin''' je α-[http://sl.wikipedia.org/wiki/Aminokislina aminokislina] s kemijsko formulo <del style="font-weight: bold; text-decoration: none;">HO2CCH</del>(<del style="font-weight: bold; text-decoration: none;">NH2</del>)CH(<del style="font-weight: bold; text-decoration: none;">CH3</del>)<del style="font-weight: bold; text-decoration: none;">CH2CH3 </del>[http://www.newworldencyclopedia.org/entry/Image:L-isoleucine-3D-sticks.png (slika L-izolevcina)]. Je [[esencialna]<del style="font-weight: bold; text-decoration: none;">] α</del>-<del style="font-weight: bold; text-decoration: none;">aminokislina, To </del>pomeni, da mora biti pridobljena s hrano v zadostnih količinah za zadovoljitev potreb telesa. [[Kodoni]], ki zapisujejo izolevcin, so AUU, AUC in AUA. </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Izolevcin''' je α-[http://sl.wikipedia.org/wiki/Aminokislina aminokislina] s kemijsko formulo <ins style="font-weight: bold; text-decoration: none;">HO<sub>2</sub>CCH</ins>(<ins style="font-weight: bold; text-decoration: none;">NH<sub>2</sub></ins>)CH(<ins style="font-weight: bold; text-decoration: none;">CH<sub>3</sub></ins>)<ins style="font-weight: bold; text-decoration: none;">CH<sub>2</sub>CH<sub>3</sub> </ins>[http://www.newworldencyclopedia.org/entry/Image:L-isoleucine-3D-sticks.png (slika L-izolevcina)]. Je [[<ins style="font-weight: bold; text-decoration: none;">esencialne aminokisline|</ins>esencialna <ins style="font-weight: bold; text-decoration: none;">aminokislina</ins>] - <ins style="font-weight: bold; text-decoration: none;">to </ins>pomeni, da mora biti pridobljena s hrano v zadostnih količinah za zadovoljitev potreb telesa. [[<ins style="font-weight: bold; text-decoration: none;">kodon|</ins>Kodoni]], ki zapisujejo izolevcin, so AUU, AUC in AUA. </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Je [http://sl.wikipedia.org/wiki/Hidrofobnost hidrofobna] aminokislina. Skupaj s [[treoninom]] je ena od dveh aminokislin, ki imata kiralni center na stranski verigi. Ima 4 stereoizomere in dva možna diastereomera <del style="font-weight: bold; text-decoration: none;">L-izolevcina</del>. V naravi obstaja v enantiomerni obliki kot (2S,3S)-2-amino-3-metilpentanojska kislina.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Je [http://sl.wikipedia.org/wiki/Hidrofobnost hidrofobna] aminokislina. Skupaj s [[<ins style="font-weight: bold; text-decoration: none;">treonin|</ins>treoninom]] je ena od dveh aminokislin, ki imata kiralni center na stranski verigi. Ima 4 stereoizomere in dva možna diastereomera. V naravi obstaja v enantiomerni obliki kot (2S,3S)-2-amino-3-metilpentanojska kislina.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Izolevcin je razvejana aminokislina. V telesu imamo tri razvejane aminokisline, to so [[izolevcin]], [[valin]] in [[levcin]]. Vse pomagajo pri obnovi <del style="font-weight: bold; text-decoration: none;">mišicam </del>po delu.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Izolevcin je razvejana aminokislina. V telesu imamo tri razvejane aminokisline, to so [[izolevcin]], [[valin]] in [[levcin]]. Vse pomagajo pri obnovi <ins style="font-weight: bold; text-decoration: none;">mišic </ins>po delu.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Ohranja stabilno raven energije s tem, da pomaga regulirati krvni sladkor<del style="font-weight: bold; text-decoration: none;">, zato ga veliko najdemo tudi v hemoglobinu</del>. Pomanjkanje izolevcina lahko povzroča simptome podobne tistim pri [http://sl.wikipedia.org/wiki/Hipoglikemija hipoglikemiji], ti pa so lahko glavoboli, omotica, utrujenost, zmedenost, razdražljivost.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Ohranja stabilno raven energije s tem, da pomaga regulirati krvni sladkor. Pomanjkanje izolevcina lahko povzroča simptome podobne tistim pri [http://sl.wikipedia.org/wiki/Hipoglikemija hipoglikemiji], ti pa so lahko glavoboli, omotica, utrujenost, zmedenost, razdražljivost.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Glede na to, da je potrebno izolevcin zaužiti, <del style="font-weight: bold; text-decoration: none;"> </del>ga najdemo v <del style="font-weight: bold; text-decoration: none;">[http://sl.wikipedia.org/wiki/Beljakovina </del>beljakovinskih<del style="font-weight: bold; text-decoration: none;">] </del>živilih, kot so oreščki, semena, mleko (veliko ga je v kazeinu), meso, jajca, ribe, leča, grah, sojine in serumske beljakovine. Za ljudi, ki so na <del style="font-weight: bold; text-decoration: none;">nizko proteinskih </del>dietah je priporočljivo uživanje dodatkov. </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Glede na to, da je potrebno izolevcin zaužiti, ga najdemo v beljakovinskih živilih, kot so oreščki, semena, mleko (veliko ga je v kazeinu), meso, jajca, ribe, leča, grah, sojine in serumske beljakovine. Za ljudi, ki so na <ins style="font-weight: bold; text-decoration: none;">nizkoproteinskih </ins>dietah je priporočljivo uživanje dodatkov. </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>V rastlinah in mikroorganizmih se sintetizira v več korakih, <del style="font-weight: bold; text-decoration: none;">začenši </del>s <del style="font-weight: bold; text-decoration: none;">piruvatsko kislino </del>in α-<del style="font-weight: bold; text-decoration: none;">ketagluturata</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>V rastlinah in mikroorganizmih se sintetizira v več korakih, <ins style="font-weight: bold; text-decoration: none;">ki se začnejo </ins>s <ins style="font-weight: bold; text-decoration: none;">[[piruvat|piruvatom]] </ins>in <ins style="font-weight: bold; text-decoration: none;">[[ketoglutarat|</ins>α-<ins style="font-weight: bold; text-decoration: none;">ketoglutaratom]]</ins>.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Encimi]], ki sodelujejo v biosintezi so: </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Encimi]], ki sodelujejo v biosintezi so: </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>1. [[<del style="font-weight: bold; text-decoration: none;">Acetolaktazna </del>sintaza]] <del style="font-weight: bold; text-decoration: none;">(poznana tudi kot acetohidroksidna kislinska sintaza)</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>1. [[<ins style="font-weight: bold; text-decoration: none;">acetolaktat </ins>sintaza]]</div></td></tr>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>2. [[<del style="font-weight: bold; text-decoration: none;">Acetilhidroksi kislinska izomernareduktaza</del>]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>2. [[<ins style="font-weight: bold; text-decoration: none;">izmeroreduktaza acetilhidroksikislin</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>3. [[<del style="font-weight: bold; text-decoration: none;">Dihidroksidna kislinska </del>dehidrataza]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>3. [[dehidrataza <ins style="font-weight: bold; text-decoration: none;">dihidroksikislin</ins>]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>4. [[<del style="font-weight: bold; text-decoration: none;">Valinska </del>aminotransferaza]]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>4. [[<ins style="font-weight: bold; text-decoration: none;">valin </ins>aminotransferaza]]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Prvič ga </del>je izoliral Ehrlich leta 1904 (iz [http://wiki.fkkt.uni-lj.si/index.php/Fibrin fibrina]<del style="font-weight: bold; text-decoration: none;">) z njegovo zgradbo</del>, <del style="font-weight: bold; text-decoration: none;">ki je bila uveljavljena 3 leta pozneje</del>, <del style="font-weight: bold; text-decoration: none;">pridobljena </del>z <del style="font-weight: bold; text-decoration: none;">degradacijo v D-izoamilamin in delujočo konsekventna </del>sintezo <del style="font-weight: bold; text-decoration: none;">skozi </del>t.i. ''Streckerjevo reakcijo'' <del style="font-weight: bold; text-decoration: none;">z D-izovaleraldehidom</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Izolevcin </ins>je <ins style="font-weight: bold; text-decoration: none;">prvi </ins>izoliral <ins style="font-weight: bold; text-decoration: none;">Felix </ins>Ehrlich leta 1904 (iz <ins style="font-weight: bold; text-decoration: none;">razgradnih produktov </ins>[http://wiki.fkkt.uni-lj.si/index.php/Fibrin fibrina], <ins style="font-weight: bold; text-decoration: none;">nekateri viri pa navajajo</ins>, <ins style="font-weight: bold; text-decoration: none;">da iz hemoglobina). Zelo zgodaj so ga pridobili tudi </ins>z <ins style="font-weight: bold; text-decoration: none;">organsko </ins>sintezo <ins style="font-weight: bold; text-decoration: none;">(s </ins>t.i. ''Streckerjevo reakcijo''<ins style="font-weight: bold; text-decoration: none;">)</ins>.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Temperatura tališča je med 286 <del style="font-weight: bold; text-decoration: none;">do 288°C</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Temperatura tališča je med 286 <ins style="font-weight: bold; text-decoration: none;">in 288 °C</ins>.</div></td></tr>
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<tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l37">Line 37:</td>
<td colspan="2" class="diff-lineno">Line 38:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://webbook.nist.gov/cgi/cbook.cgi?ID=C73325&Units=SI&Mask=1E9F</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://webbook.nist.gov/cgi/cbook.cgi?ID=C73325&Units=SI&Mask=1E9F</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://books.google.si/books?id=JzArAAAAYAAJ&pg=PA10&dq=isoleucine&hl=sl&sa=X&ei=3EgDT9e8KcOr-QbR8IzGAQ&ved=0CDYQ6AEwAg#v=onepage&q=isoleucine&f=false</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://books.google.si/books?id=qgilcEBLF6QC&pg=PT217&dq=isoleucine&hl=sl&sa=X&ei=3EgDT9e8KcOr-QbR8IzGAQ&ved=0CGMQ6AEwCg#v=onepage&q=isoleucine&f=false</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://www.raysahelian.com/isoleucine.html</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">== Zunanje povezave ==</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://sl.wikipedia.org/wiki/Aminokislina</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://www.newworldencyclopedia.org/entry/Image:L-isoleucine-3D-sticks.png</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://sl.wikipedia.org/wiki/Hidrofobnost</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://sl.wikipedia.org/wiki/Hipoglikemija</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://sl.wikipedia.org/wiki/Beljakovina</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">http://wiki.fkkt.uni-lj.si/index.php/Fibrin</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr>
</table>
MDolinar
https://wiki.fkkt.uni-lj.si/index.php?title=Izolevcin&diff=6752&oldid=prev
Erika.Urbiha: New page: '''Izolevcin''' je α-[http://sl.wikipedia.org/wiki/Aminokislina aminokislina] s kemijsko formulo HO2CCH(NH2)CH(CH3)CH2CH3 [http://www.newworldencyclopedia.org/entry/Image:L-isoleucine-3D-...
2012-01-04T12:52:06Z
<p>New page: '''Izolevcin''' je α-[http://sl.wikipedia.org/wiki/Aminokislina aminokislina] s kemijsko formulo HO2CCH(NH2)CH(CH3)CH2CH3 [http://www.newworldencyclopedia.org/entry/Image:L-isoleucine-3D-...</p>
<p><b>New page</b></p><div>'''Izolevcin''' je α-[http://sl.wikipedia.org/wiki/Aminokislina aminokislina] s kemijsko formulo HO2CCH(NH2)CH(CH3)CH2CH3 [http://www.newworldencyclopedia.org/entry/Image:L-isoleucine-3D-sticks.png (slika L-izolevcina)]. Je [[esencialna]] α-aminokislina, To pomeni, da mora biti pridobljena s hrano v zadostnih količinah za zadovoljitev potreb telesa. [[Kodoni]], ki zapisujejo izolevcin, so AUU, AUC in AUA. <br />
<br />
Je [http://sl.wikipedia.org/wiki/Hidrofobnost hidrofobna] aminokislina. Skupaj s [[treoninom]] je ena od dveh aminokislin, ki imata kiralni center na stranski verigi. Ima 4 stereoizomere in dva možna diastereomera L-izolevcina. V naravi obstaja v enantiomerni obliki kot (2S,3S)-2-amino-3-metilpentanojska kislina.<br />
<br />
Izolevcin je razvejana aminokislina. V telesu imamo tri razvejane aminokisline, to so [[izolevcin]], [[valin]] in [[levcin]]. Vse pomagajo pri obnovi mišicam po delu.<br />
<br />
Ohranja stabilno raven energije s tem, da pomaga regulirati krvni sladkor, zato ga veliko najdemo tudi v hemoglobinu. Pomanjkanje izolevcina lahko povzroča simptome podobne tistim pri [http://sl.wikipedia.org/wiki/Hipoglikemija hipoglikemiji], ti pa so lahko glavoboli, omotica, utrujenost, zmedenost, razdražljivost.<br />
<br />
Glede na to, da je potrebno izolevcin zaužiti, ga najdemo v [http://sl.wikipedia.org/wiki/Beljakovina beljakovinskih] živilih, kot so oreščki, semena, mleko (veliko ga je v kazeinu), meso, jajca, ribe, leča, grah, sojine in serumske beljakovine. Za ljudi, ki so na nizko proteinskih dietah je priporočljivo uživanje dodatkov. <br />
<br />
V rastlinah in mikroorganizmih se sintetizira v več korakih, začenši s piruvatsko kislino in α-ketagluturata.<br />
[[Encimi]], ki sodelujejo v biosintezi so: <br />
<br />
1. [[Acetolaktazna sintaza]] (poznana tudi kot acetohidroksidna kislinska sintaza)<br />
<br />
2. [[Acetilhidroksi kislinska izomernareduktaza]]<br />
<br />
3. [[Dihidroksidna kislinska dehidrataza]]<br />
<br />
4. [[Valinska aminotransferaza]]<br />
<br />
Prvič ga je izoliral Ehrlich leta 1904 (iz [http://wiki.fkkt.uni-lj.si/index.php/Fibrin fibrina]) z njegovo zgradbo, ki je bila uveljavljena 3 leta pozneje, pridobljena z degradacijo v D-izoamilamin in delujočo konsekventna sintezo skozi t.i. ''Streckerjevo reakcijo'' z D-izovaleraldehidom.<br />
Temperatura tališča je med 286 do 288°C.<br />
<br />
<br />
== Viri ==<br />
<br />
http://www.peptideguide.com/amino-acids/isoleucine.html<br />
<br />
http://www.newworldencyclopedia.org/entry/Isoleucine<br />
<br />
http://en.wikipedia.org/w/index.php?title=Isoleucine&oldid=136971877<br />
<br />
http://www.biology.arizona.edu/biochemistry/problem_sets/aa/Isoleusine.html<br />
<br />
http://www.springboard4health.com/notebook/proteins_isoleucine.html<br />
<br />
http://webbook.nist.gov/cgi/cbook.cgi?ID=C73325&Units=SI&Mask=1E9F<br />
<br />
http://books.google.si/books?id=JzArAAAAYAAJ&pg=PA10&dq=isoleucine&hl=sl&sa=X&ei=3EgDT9e8KcOr-QbR8IzGAQ&ved=0CDYQ6AEwAg#v=onepage&q=isoleucine&f=false<br />
<br />
http://books.google.si/books?id=qgilcEBLF6QC&pg=PT217&dq=isoleucine&hl=sl&sa=X&ei=3EgDT9e8KcOr-QbR8IzGAQ&ved=0CGMQ6AEwCg#v=onepage&q=isoleucine&f=false<br />
<br />
http://www.raysahelian.com/isoleucine.html<br />
<br />
<br />
<br />
== Zunanje povezave ==<br />
http://sl.wikipedia.org/wiki/Aminokislina<br />
<br />
http://www.newworldencyclopedia.org/entry/Image:L-isoleucine-3D-sticks.png<br />
<br />
http://sl.wikipedia.org/wiki/Hidrofobnost<br />
<br />
http://sl.wikipedia.org/wiki/Hipoglikemija<br />
<br />
http://sl.wikipedia.org/wiki/Beljakovina<br />
<br />
http://wiki.fkkt.uni-lj.si/index.php/Fibrin<br />
<br />
[[Category:LEX]]</div>
Erika.Urbiha