https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Kimotripsin
Kimotripsin - Revision history
2026-04-10T04:13:37Z
Revision history for this page on the wiki
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https://wiki.fkkt.uni-lj.si/index.php?title=Kimotripsin&diff=3051&oldid=prev
MDolinar at 09:39, 19 February 2010
2010-02-19T09:39:11Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 09:39, 19 February 2010</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Kimotripsin je prebavni encim, ki se sintetizira v trebušni slinavki. Pripada skupini encimov, ki se imenujejo serinske proteaze, med katere sodita tudi tripsin in elastaza. Ti encimi cepijo proteine (beljakovine) na manjše polipeptide, pri čemer ima ključno katalitično vlogo serinski ostanek v aktivnem mestu encima. Kimotripsin hidrolizira peptidno vez aminokislin s hidrofobno stransko verigo kot so: triptofan, tirozin in fenilalanin.</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Kimotripsin je aktiven pri nevtralnem pH. Ker delno prebavljena hrana iz želodca prihaja v dvanajstnik zelo kisla, je treba želodčno kislino HCl(solna kislina) nevtralizirati z izločki trebušne slinavke. Serin v aktivnem mestu je mogoče blokirati z različnimi reagenti, npr. z diizofosfofluoridom in tako zaustaviti aktivnost serinskih proteinaz. Razen serina v mehanizmu cepitve peptidne vezi sodelujeta še dva eminokislinska ostanka, tako da skupaj sestavljajo tako imenovano 'katalitično triado'.</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Kimotripsin v trebušni slinavki je v neaktivnem stanju kot kimotripsinogen, ko pride v prebavni trakt, pa ga tripsin aktivira v kimotripsin. Kimotripsin deluje podobno kot tripsin, vendar je nekoliko manj aktiven. Kimotripsin in tripsin delujeta lažje na denaturirane (s kuhanjem ali s prebavo v želodcu) beljakovine.</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Kimotripsin (chymotrypsin) je prebavni encim ,ki deluje kot katalizator. Nahaja v trebušni slinavki in pripada družini encimov, ki se imenujejo serinske proteaze in vsebujejo tripsin. Ti encimi cepijo proteine(beljakovine) na manjše polipeptide, na strani verige serina igrajo katalitično vlogo v cepljenju. Kimotripsin hidrolizira peptidno vez aminokisline z dolgo hidrofobno stranjo verige kot so: triptofan, tirozin in fenilalanin.</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">[</ins>http://www.<ins style="font-weight: bold; text-decoration: none;">bmb</ins>.<ins style="font-weight: bold; text-decoration: none;">psu</ins>.edu/<ins style="font-weight: bold; text-decoration: none;">faculty</ins>/<ins style="font-weight: bold; text-decoration: none;">tan</ins>/<ins style="font-weight: bold; text-decoration: none;">lab</ins>/<ins style="font-weight: bold; text-decoration: none;">gallery</ins>/<ins style="font-weight: bold; text-decoration: none;">chymo_ribbon2</ins>.<ins style="font-weight: bold; text-decoration: none;">jpg Struktura kimotripsina]</ins></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Kimotripsin je aktiven pri nevtralnem pH, ki se doseže z nevtralizacijo HCl(solna kislina) iz NaHCO3(soda bikarbona) in iz soka trebusne slinavke. Solna kislina(HCl) se nahaja v želodčnem soku. Tripsin, elastaza in kimotripsin vsebujejo v svoji strukturi serinski ostanek. Reagenti, npr. (diizofosfoflorid), ki interagirajo s serinom, na tak nacin inaktivirajo te encime. </del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Kimotripsin v trebušni slinavki je v neaktivnem stanju kot kimotripsinogen, ko pride v prebavni trakt (črevo), ga tripsin aktivira v kimotripsin. Kimotripsin deluje podobno kot tripsin vendar malce slabše. Kimotripsin in tirozin delujeta lažje na denaturirane (s kuhanjem ali s prebavo v želodcu) beljakovine.</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Dodatno slikovno gradivo in razlaga gesla ter viri so na voljo na sledečih spletnih straneh:</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"> </del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">1. http://images.google.si/images?gbv=2&hl=sl&ei=AxJDS_2eGNWcsAap8qmDAg&sa=X&oi=spell&resnum=0&ct=result&cd=1&q=chymotrypsin&spell=1&start=0</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">2.</del>http://www.<del style="font-weight: bold; text-decoration: none;">bio</del>.<del style="font-weight: bold; text-decoration: none;">davidson</del>.edu/<del style="font-weight: bold; text-decoration: none;">Courses</del>/<del style="font-weight: bold; text-decoration: none;">Molbio</del>/<del style="font-weight: bold; text-decoration: none;">MolStudents</del>/<del style="font-weight: bold; text-decoration: none;">spring2003</del>/<del style="font-weight: bold; text-decoration: none;">MaloneyH/chymotrypsintemplate.html</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">3</del>. <del style="font-weight: bold; text-decoration: none;">http://www.medenosrce.net/pogled.asp?ID=470</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td colspan="2" class="diff-side-added"></td></tr>
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MDolinar
https://wiki.fkkt.uni-lj.si/index.php?title=Kimotripsin&diff=2448&oldid=prev
Sabri at 10:35, 5 January 2010
2010-01-05T10:35:10Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:35, 5 January 2010</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Kimotripsin v trebušni slinavki je v neaktivnem stanju kot kimotripsinogen, ko pride v prebavni trakt (črevo), ga tripsin aktivira v kimotripsin. Kimotripsin deluje podobno kot tripsin vendar malce slabše. Kimotripsin in tirozin delujeta lažje na denaturirane (s kuhanjem ali s prebavo v želodcu) beljakovine.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Kimotripsin v trebušni slinavki je v neaktivnem stanju kot kimotripsinogen, ko pride v prebavni trakt (črevo), ga tripsin aktivira v kimotripsin. Kimotripsin deluje podobno kot tripsin vendar malce slabše. Kimotripsin in tirozin delujeta lažje na denaturirane (s kuhanjem ali s prebavo v želodcu) beljakovine.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Viri:</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Dodatno slikovno gradivo in razlaga gesla <del style="font-weight: bold; text-decoration: none;">sta </del>na voljo na sledečih spletnih straneh: </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Dodatno slikovno gradivo in razlaga gesla <ins style="font-weight: bold; text-decoration: none;">ter viri so </ins>na voljo na sledečih spletnih straneh:</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>http://images.google.si/images?gbv=2&hl=sl&ei=AxJDS_2eGNWcsAap8qmDAg&sa=X&oi=spell&resnum=0&ct=result&cd=1&q=chymotrypsin&spell=1&start=0</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"> </ins></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/MaloneyH/chymotrypsintemplate.html</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">1. </ins>http://images.google.si/images?gbv=2&hl=sl&ei=AxJDS_2eGNWcsAap8qmDAg&sa=X&oi=spell&resnum=0&ct=result&cd=1&q=chymotrypsin&spell=1&start=0</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>http://www.medenosrce.net/pogled.asp?ID=470</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">2.</ins>http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/MaloneyH/chymotrypsintemplate.html</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">3. </ins>http://www.medenosrce.net/pogled.asp?ID=470</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Pripravila: Sabrina Čermelj</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Pripravila: Sabrina Čermelj</div></td></tr>
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Sabri
https://wiki.fkkt.uni-lj.si/index.php?title=Kimotripsin&diff=2443&oldid=prev
Sabri at 10:30, 5 January 2010
2010-01-05T10:30:15Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:30, 5 January 2010</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Viri:</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Viri:</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Dodatno slikovno gradivo in razlaga gesla sta na voljo na sledečih spletnih straneh: </ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://images.google.si/images?gbv=2&hl=sl&ei=AxJDS_2eGNWcsAap8qmDAg&sa=X&oi=spell&resnum=0&ct=result&cd=1&q=chymotrypsin&spell=1&start=0</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://images.google.si/images?gbv=2&hl=sl&ei=AxJDS_2eGNWcsAap8qmDAg&sa=X&oi=spell&resnum=0&ct=result&cd=1&q=chymotrypsin&spell=1&start=0</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/MaloneyH/chymotrypsintemplate.html</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/MaloneyH/chymotrypsintemplate.html</div></td></tr>
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Sabri
https://wiki.fkkt.uni-lj.si/index.php?title=Kimotripsin&diff=2441&oldid=prev
Sabri: New page: Kimotripsin (chymotrypsin) je prebavni encim ,ki deluje kot katalizator. Nahaja v trebušni slinavki in pripada družini encimov, ki se imenujejo serinske proteaze in vsebujejo trips...
2010-01-05T10:25:49Z
<p>New page: Kimotripsin (chymotrypsin) je prebavni encim ,ki deluje kot katalizator. Nahaja v trebušni slinavki in pripada družini encimov, ki se imenujejo serinske proteaze in vsebujejo trips...</p>
<p><b>New page</b></p><div><br />
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Kimotripsin (chymotrypsin) je prebavni encim ,ki deluje kot katalizator. Nahaja v trebušni slinavki in pripada družini encimov, ki se imenujejo serinske proteaze in vsebujejo tripsin. Ti encimi cepijo proteine(beljakovine) na manjše polipeptide, na strani verige serina igrajo katalitično vlogo v cepljenju. Kimotripsin hidrolizira peptidno vez aminokisline z dolgo hidrofobno stranjo verige kot so: triptofan, tirozin in fenilalanin.<br />
Kimotripsin je aktiven pri nevtralnem pH, ki se doseže z nevtralizacijo HCl(solna kislina) iz NaHCO3(soda bikarbona) in iz soka trebusne slinavke. Solna kislina(HCl) se nahaja v želodčnem soku. Tripsin, elastaza in kimotripsin vsebujejo v svoji strukturi serinski ostanek. Reagenti, npr. (diizofosfoflorid), ki interagirajo s serinom, na tak nacin inaktivirajo te encime. <br />
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Kimotripsin v trebušni slinavki je v neaktivnem stanju kot kimotripsinogen, ko pride v prebavni trakt (črevo), ga tripsin aktivira v kimotripsin. Kimotripsin deluje podobno kot tripsin vendar malce slabše. Kimotripsin in tirozin delujeta lažje na denaturirane (s kuhanjem ali s prebavo v želodcu) beljakovine.<br />
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Viri:<br />
http://images.google.si/images?gbv=2&hl=sl&ei=AxJDS_2eGNWcsAap8qmDAg&sa=X&oi=spell&resnum=0&ct=result&cd=1&q=chymotrypsin&spell=1&start=0<br />
http://www.bio.davidson.edu/Courses/Molbio/MolStudents/spring2003/MaloneyH/chymotrypsintemplate.html<br />
http://www.medenosrce.net/pogled.asp?ID=470<br />
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Pripravila: Sabrina Čermelj<br />
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[[Category:LEX]]</div>
Sabri