https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Transkripcijski_faktorji 2026-04-06T23:37:56Z Revision history for this page on the wiki MediaWiki 1.39.3 https://wiki.fkkt.uni-lj.si/index.php?title=Transkripcijski_faktorji&diff=4993&oldid=prev 2010-12-14T20:49:28Z

<p><span dir="auto"><span class="autocomment">Zunanje povezave</span></span></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 20:49, 14 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l17">Line 17:</td> <td colspan="2" class="diff-lineno">Line 17:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Zunanje povezave ==  </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Zunanje povezave ==  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://atlasgeneticsoncology.org/Educ/TFactorsEng.html</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://atlasgeneticsoncology.org/Educ/TFactorsEng.html</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://biotech.about.com/od/proteinengineering/f/transcriptfact.htm</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://biotech.about.com/od/proteinengineering/f/transcriptfact.htm</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.scientificamerican.com/blog/post.cfm?id=transcription-factors-boost-genetic-2010-03-18</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.scientificamerican.com/blog/post.cfm?id=transcription-factors-boost-genetic-2010-03-18</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr> </table>

Andreja.p https://wiki.fkkt.uni-lj.si/index.php?title=Transkripcijski_faktorji&diff=4992&oldid=prev 2010-12-14T20:49:13Z

<p><span dir="auto"><span class="autocomment">Viri</span></span></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 20:49, 14 December 2010</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l10">Line 10:</td> <td colspan="2" class="diff-lineno">Line 10:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Viri ==  </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Viri ==  </div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://en.wikipedia.org/wiki/Transcription_factor</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://en.wikipedia.org/wiki/Transcription_factor</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://atlasgeneticsoncology.org/Deep/TranscripFactorsID20043.html</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://atlasgeneticsoncology.org/Deep/TranscripFactorsID20043.html</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.iscid.org/encyclopedia/Transcription_Factor</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>http://www.iscid.org/encyclopedia/Transcription_Factor</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> </table>

Andreja.p https://wiki.fkkt.uni-lj.si/index.php?title=Transkripcijski_faktorji&diff=4991&oldid=prev 2010-12-14T20:46:48Z

<p>New page: &#039;&#039;&#039;Transkripcijski faktor&#039;&#039;&#039; je <a href="/index.php?title=Beljakovina&amp;action=edit&amp;redlink=1" class="new" title="Beljakovina (page does not exist)">beljakovina</a>, ki je potrebna za pričetek <a href="/index.php?title=Transkripcija&amp;action=edit&amp;redlink=1" class="new" title="Transkripcija (page does not exist)">transkripcije</a> (prepisovanja), vendar ni del polimeraznega kompleksa. Veže razpoznavni elemen...</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Transkripcijski faktor&#039;&#039;&#039; je [[beljakovina]], ki je potrebna za pričetek [[transkripcija|transkripcije]] (prepisovanja), vendar ni del polimeraznega kompleksa. Veže razpoznavni element [[DNK]]. Preko protein-protein interakcij sodeluje z drugimi transkripcijskimi faktorji, s [[s transkripcijo povezani faktor|transkripcijo povezanimi faktorji (TAFi)]] ali z [[RNK-polimeraza|RNK-polimerazo]]. Ločimo dva splošna tipa transkripcijskih faktorjev:<br /> * bazalne transkripcijske faktorje ter <br /> * faktorje, ki kontrolirajo izražanje posameznih [[gen]]ov in so zato odgovorni za uravnavanje genske ekspresije.<br /> <br /> Transkripcijski faktorji so potrebni za pričetek prepisovanja z določenega [[promotor]]ja ali niza [[promotor]]jev. Sestavljeni so iz več funkcionalnih domen.<br /> <br /> Najbolje preučevani transkripcijski faktorji so transkripcijski aktivatorji. Le-ti se vežejo na regulatorna [[DNK]]-zaporedja in stimulirajo prepisovanje. Na splošno naj bi bili ti faktorji sestavljeni iz dveh domen; ena regija proteina se specifično veže na DNK, druga pa aktivira transkripcijo z interakcijo ostalih komponent [[transkripcijske mašinerije]]. Osnovna funkcija DNK vezavne domene je »zasidranje« transkripcijskih faktorjev na pravilno mesto DNK; aktivacijska domena nato neodvisno stimulira transkripcijo s povezovanjem ostalih proteinov.<br /> Mnogo DNK vezavnih domen teh proteinov je sorodnih. Domene, imenovane [[cinkov prst]], vsebujejo ponovitve [[cistein]]skih in [[histidin]]skih ostankov, ki vežejo [[cink]]ove ione in se pri tem zvijejo v »zankasto« strukturo (»prst«), ki veže DNK. Te domene so odkrili pri [[TFIIIA]] in [[Sp1]]. Te aktivacijske domene naj bi uravnavale transkripcijo tako, da interagirajo z bazalnimi transkripcijskimi faktorji (npr. [[TFIIB]] ali [[TFIID]]). Tako naj bi omogočili združitev transkripcijskega kompleksa na promotor [http://AtlasGeneticsOncology.org/Educ/TFactorsEng.html 1]<br /> <br /> == Viri == <br /> http://en.wikipedia.org/wiki/Transcription_factor<br /> http://atlasgeneticsoncology.org/Deep/TranscripFactorsID20043.html<br /> http://www.iscid.org/encyclopedia/Transcription_Factor<br /> <br /> == Zunanje povezave == <br /> http://atlasgeneticsoncology.org/Educ/TFactorsEng.html<br /> http://biotech.about.com/od/proteinengineering/f/transcriptfact.htm<br /> http://www.scientificamerican.com/blog/post.cfm?id=transcription-factors-boost-genetic-2010-03-18<br /> <br /> [[Category:LEX]]</div>

Andreja.p