https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Tropomodulin
Tropomodulin - Revision history
2026-05-23T12:14:07Z
Revision history for this page on the wiki
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https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=5339&oldid=prev
MDolinar at 10:51, 4 February 2011
2011-02-04T10:51:34Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:51, 4 February 2011</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;"></del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Tropomodulin''' je tropomiozin-vezavni protein, prvotno izoliran iz človeškega eritrocitov. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Tropomodulin''' je tropomiozin-vezavni protein, prvotno izoliran iz človeškega eritrocitov. </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Tropomodulin je protein globularne oblike <del style="font-weight: bold; text-decoration: none;">z molekulsko maso 43 kDa, ki se veže na en konec tropomiozinske paličaste molekule. Sodeluje pri stabilizaciji aktinskega protofilamenta.Skica molekule:</del>[http://www.ncbi.nlm.nih.gov/books/NBK21493/figure/A5132/?report=objectonly]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Tropomodulin je protein globularne oblike <ins style="font-weight: bold; text-decoration: none;">(</ins>[http://www.ncbi.nlm.nih.gov/books/NBK21493/figure/A5132/?report=objectonly <ins style="font-weight: bold; text-decoration: none;">skica molekule</ins>]<ins style="font-weight: bold; text-decoration: none;">) z molekulsko maso 43 kDa, ki se veže na en konec tropomiozinske paličaste molekule. Sodeluje pri stabilizaciji aktinskega protofilamenta.</ins></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Imenujemo ga tudi pokrovni protein. Je beljakovina, ki se veže na konec <ins style="font-weight: bold; text-decoration: none;">[[aktin|</ins>aktina<ins style="font-weight: bold; text-decoration: none;">]] </ins>ter ureja dolžino aktinskih filamentov v mišičnih in ne-mišičnih celicah. Deluje v prisotnosti <ins style="font-weight: bold; text-decoration: none;">[[aktin|</ins>aktina<ins style="font-weight: bold; text-decoration: none;">]]</ins>, <ins style="font-weight: bold; text-decoration: none;">[[tropomiozin|</ins>tropomiozina<ins style="font-weight: bold; text-decoration: none;">]] </ins>in <ins style="font-weight: bold; text-decoration: none;">[[nebulin|</ins>nebulina<ins style="font-weight: bold; text-decoration: none;">]] </ins>ter tako zavira <ins style="font-weight: bold; text-decoration: none;">raztezanje mikrofilamentov</ins>.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Imenujemo ga tudi pokrovni protein. Je beljakovina, ki se veže na konec aktina ter ureja dolžino aktinskih filamentov v mišičnih in ne-mišičnih celicah. Deluje v prisotnosti aktina, tropomiozina in nebulina ter tako zavira <del style="font-weight: bold; text-decoration: none;">mikrofilamentni raztezek</del>. </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"> </ins></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Tropomodulin je pokrovni protein za koničaste konce aktinskega filamenta in je povezan s prostimi, koničastimi konci iz tankih filamentov v progastih mišicah, kjer se veže na tropomiozin in aktin.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Tropomodulin je pokrovni protein za koničaste konce aktinskega filamenta in je povezan s prostimi, koničastimi konci iz tankih filamentov v progastih mišicah, kjer se veže na tropomiozin in aktin. Tropomodulin je tropomiozinska <ins style="font-weight: bold; text-decoration: none;">regulatorna </ins>beljakovina, ki se veže na eritrocit in blokira <ins style="font-weight: bold; text-decoration: none;">povezovanje </ins>tropomiozina <ins style="font-weight: bold; text-decoration: none;">v smeri glava - rep </ins>vzdolž aktinskih filamentov. Omejena proteoliza kaže na to, da je protein sestavljen iz dveh domen. Nestrukturirana <ins style="font-weight: bold; text-decoration: none;">tropomiozin-vezavna </ins>regija <ins style="font-weight: bold; text-decoration: none;">je </ins>na <ins style="font-weight: bold; text-decoration: none;">N-</ins>koncu<ins style="font-weight: bold; text-decoration: none;">. Druga regija</ins>, ki je v bližini skrajnega C<ins style="font-weight: bold; text-decoration: none;">-konca, je od tropomiozina </ins>neodvisna pokrovna domena <ins style="font-weight: bold; text-decoration: none;">in veže </ins>aktin.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Kontrola dolžine in dinamike <ins style="font-weight: bold; text-decoration: none;">aktinskih filamentov </ins>je pomembna za gibljivost celic in <ins style="font-weight: bold; text-decoration: none;">celično zgradbo, to pa </ins>delno <ins style="font-weight: bold; text-decoration: none;">urejajo omejevalni proteini</ins>, ki zavirajo raztezek in depolimerizacijo na hitro in počasi rastočih koncih. </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Tropomodulin je tropomiozinska <del style="font-weight: bold; text-decoration: none;"> regulativna </del>beljakovina, ki se veže na eritrocit <del style="font-weight: bold; text-decoration: none;"> </del>in blokira <del style="font-weight: bold; text-decoration: none;">združenje od glave do repa </del>tropomiozina vzdolž aktinskih filamentov. Omejena proteoliza kaže na to, da je protein sestavljen iz dveh domen. Nestrukturirana <del style="font-weight: bold; text-decoration: none;">tropomiozinska zavezujoča </del>regija na koncu <del style="font-weight: bold; text-decoration: none;">N ima aktinski poudarjen konec omejevanja dejavnosti</del>, ki je <del style="font-weight: bold; text-decoration: none;">urejena s tropomiozinsko prevleko iz aktinskega filamenta. Druga regija se nahaja </del>v bližini skrajnega C<del style="font-weight: bold; text-decoration: none;">. Ta tropomiozin </del>neodvisna pokrovna domena <del style="font-weight: bold; text-decoration: none;">pokriva čisti </del>aktin.</div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Kontrola <del style="font-weight: bold; text-decoration: none;"> aktinske filamentne </del>dolžine in dinamike je pomembna za gibljivost celic in <del style="font-weight: bold; text-decoration: none;">zgradbe in je </del>delno <del style="font-weight: bold; text-decoration: none;">urejena z limitiranimi beljakovinami</del>, ki zavirajo raztezek in depolimerizacijo na hitro in počasi rastočih koncih. </div></td><td colspan="2" class="diff-side-added"></td></tr>
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MDolinar
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4737&oldid=prev
Milan Obradović at 13:54, 12 December 2010
2010-12-12T13:54:15Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:54, 12 December 2010</td>
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<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Tropomodulin''' je tropomiozin-vezavni protein, prvotno izoliran iz človeškega eritrocitov. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Tropomodulin''' je tropomiozin-vezavni protein, prvotno izoliran iz človeškega eritrocitov. </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Tropomodulin je protein globularne oblike z molekulsko maso 43 kDa, ki se veže na en konec tropomiozinske paličaste molekule. Sodeluje pri stabilizaciji aktinskega protofilamenta.Skica molekule:[http://www.ncbi.nlm.nih.gov/books/NBK21493/figure/A5132/?report=objectonly]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Tropomodulin je protein globularne oblike z molekulsko maso 43 kDa, ki se veže na en konec tropomiozinske paličaste molekule. Sodeluje pri stabilizaciji aktinskega protofilamenta.Skica molekule:[http://www.ncbi.nlm.nih.gov/books/NBK21493/figure/A5132/?report=objectonly]</div></td></tr>
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Milan Obradović
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4736&oldid=prev
Milan Obradović at 13:52, 12 December 2010
2010-12-12T13:52:28Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:52, 12 December 2010</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">• </del>http://www.ncbi.nlm.nih.gov/books/NBK21493/</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">* </ins>http://www.ncbi.nlm.nih.gov/books/NBK21493/</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">• </del>http://jcs.biologists.org/cgi/content/abstract/109/9/2299</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">* </ins>http://jcs.biologists.org/cgi/content/abstract/109/9/2299</div></td></tr>
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Milan Obradović
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4733&oldid=prev
Milan Obradović at 13:51, 12 December 2010
2010-12-12T13:51:17Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>• http://www.ncbi.nlm.nih.gov/books/NBK21493/</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>• http://www.ncbi.nlm.nih.gov/books/NBK21493/</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>• <del style="font-weight: bold; text-decoration: none;">[</del>http://jcs.biologists.org/cgi/content/abstract/109/9/2299<del style="font-weight: bold; text-decoration: none;">]</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>• http://jcs.biologists.org/cgi/content/abstract/109/9/2299</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>• <del style="font-weight: bold; text-decoration: none;">[</del>http://jcb.rupress.org/content/189/1/95.abstract<del style="font-weight: bold; text-decoration: none;">]</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>• http://jcb.rupress.org/content/189/1/95.abstract</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr>
</table>
Milan Obradović
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4732&oldid=prev
Milan Obradović at 13:50, 12 December 2010
2010-12-12T13:50:54Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
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<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:50, 12 December 2010</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l11">Line 11:</td>
<td colspan="2" class="diff-lineno">Line 11:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Viri ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Viri ==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>• <del style="font-weight: bold; text-decoration: none;">[</del>http://www.ncbi.nlm.nih.gov/books/NBK21493/<del style="font-weight: bold; text-decoration: none;">www.ncbi.nlm.nih.gov/books/NBK21493/]</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>• http://www.ncbi.nlm.nih.gov/books/NBK21493/</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>• [http://jcs.biologists.org/cgi/content/abstract/109/9/2299]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>• [http://jcs.biologists.org/cgi/content/abstract/109/9/2299]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>• [http://jcb.rupress.org/content/189/1/95.abstract]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>• [http://jcb.rupress.org/content/189/1/95.abstract]</div></td></tr>
</table>
Milan Obradović
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4727&oldid=prev
Milan Obradović at 13:47, 12 December 2010
2010-12-12T13:47:46Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:47, 12 December 2010</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l11">Line 11:</td>
<td colspan="2" class="diff-lineno">Line 11:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Viri ==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>== Viri ==</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>•[http://www.ncbi.nlm.nih.gov/books/NBK21493/]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>• [http:/<ins style="font-weight: bold; text-decoration: none;">/www.ncbi.nlm.nih.gov/books/NBK21493</ins>/www.ncbi.nlm.nih.gov/books/NBK21493/]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>•[http://jcs.biologists.org/cgi/content/abstract/109/9/2299]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>• [http://jcs.biologists.org/cgi/content/abstract/109/9/2299]</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>•[http://jcb.rupress.org/content/189/1/95.abstract]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>• [http://jcb.rupress.org/content/189/1/95.abstract]</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr>
</table>
Milan Obradović
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4713&oldid=prev
Milan Obradović at 12:36, 12 December 2010
2010-12-12T12:36:09Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:36, 12 December 2010</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l8">Line 8:</td>
<td colspan="2" class="diff-lineno">Line 8:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Kontrola aktinske filamentne dolžine in dinamike je pomembna za gibljivost celic in zgradbe in je delno urejena z limitiranimi beljakovinami, ki zavirajo raztezek in depolimerizacijo na hitro in počasi rastočih koncih. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Kontrola aktinske filamentne dolžine in dinamike je pomembna za gibljivost celic in zgradbe in je delno urejena z limitiranimi beljakovinami, ki zavirajo raztezek in depolimerizacijo na hitro in počasi rastočih koncih. </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">'''</del>Viri<del style="font-weight: bold; text-decoration: none;">'''</del></div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[http://www.ncbi.nlm.nih.gov/books/NBK21493/]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== </ins>Viri <ins style="font-weight: bold; text-decoration: none;">==</ins></div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>[http://jcs.biologists.org/cgi/content/abstract/109/9/2299]</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">•</ins>[http://www.ncbi.nlm.nih.gov/books/NBK21493/]</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">•</ins>[http://jcs.biologists.org/cgi/content/abstract/109/9/2299]</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">•[http://jcb.rupress.org/content/189/1/95.abstract]</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:LEX]]</div></td></tr>
</table>
Milan Obradović
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4708&oldid=prev
Milan Obradović at 12:23, 12 December 2010
2010-12-12T12:23:32Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:23, 12 December 2010</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l12">Line 12:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://jcs.biologists.org/cgi/content/abstract/109/9/2299]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://jcs.biologists.org/cgi/content/abstract/109/9/2299]</div></td></tr>
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Milan Obradović
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4707&oldid=prev
Milan Obradović at 12:17, 12 December 2010
2010-12-12T12:17:21Z
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://www.ncbi.nlm.nih.gov/books/NBK21493/]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[http://www.ncbi.nlm.nih.gov/books/NBK21493/]</div></td></tr>
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Milan Obradović
https://wiki.fkkt.uni-lj.si/index.php?title=Tropomodulin&diff=4706&oldid=prev
Milan Obradović at 12:06, 12 December 2010
2010-12-12T12:06:42Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:06, 12 December 2010</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Tropomodulin je beljakovina, ki se veže <del style="font-weight: bold; text-decoration: none;">koncu </del>aktina<del style="font-weight: bold; text-decoration: none;">, ki </del>ureja dolžino aktinskih filamentov v <del style="font-weight: bold; text-decoration: none;">mišicah </del>in ne-mišičnih celicah. Deluje v prisotnosti tropomiozina in nebulina zavira <del style="font-weight: bold; text-decoration: none;">microfilament </del>raztezek. <del style="font-weight: bold; text-decoration: none;">Inhibicija tropomodulin limitiranja </del>dejavnosti <del style="font-weight: bold; text-decoration: none;">vodi do dramatičnega porasta </del>v <del style="font-weight: bold; text-decoration: none;">tanki filamentski dolžini </del>z <del style="font-weight: bold; text-decoration: none;">žarilno nitko iz svojih koncev</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">'''</ins>Tropomodulin<ins style="font-weight: bold; text-decoration: none;">''' </ins>je <ins style="font-weight: bold; text-decoration: none;">tropomiozin-vezavni protein, prvotno izoliran iz človeškega eritrocitov. </ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Tropomodulin je protein globularne oblike z molekulsko maso 43 kDa, ki se veže na en konec tropomiozinske paličaste molekule. Sodeluje pri stabilizaciji aktinskega protofilamenta.Skica molekule:[http://www.ncbi.nlm.nih.gov/books/NBK21493/figure/A5132/?report=objectonly]</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Imenujemo ga tudi pokrovni protein. Je </ins>beljakovina, ki se veže <ins style="font-weight: bold; text-decoration: none;">na konec </ins>aktina <ins style="font-weight: bold; text-decoration: none;">ter </ins>ureja dolžino aktinskih filamentov v <ins style="font-weight: bold; text-decoration: none;">mišičnih </ins>in ne-mišičnih celicah. Deluje v prisotnosti <ins style="font-weight: bold; text-decoration: none;">aktina, </ins>tropomiozina in nebulina <ins style="font-weight: bold; text-decoration: none;">ter tako </ins>zavira <ins style="font-weight: bold; text-decoration: none;">mikrofilamentni </ins>raztezek. </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Tropomodulin je pokrovni protein za koničaste konce aktinskega filamenta in je povezan s prostimi, koničastimi konci iz tankih filamentov v progastih mišicah, kjer se veže na tropomiozin in aktin.</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div> </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Tropomodulin je tropomiozinska regulativna beljakovina, ki se veže na eritrocit in blokira združenje od glave do repa tropomiozina vzdolž aktinskih filamentov. Omejena proteoliza kaže na to, da je protein sestavljen iz dveh domen. Nestrukturirana tropomiozinska zavezujoča regija na koncu N ima aktinski poudarjen konec omejevanja </ins>dejavnosti<ins style="font-weight: bold; text-decoration: none;">, ki je urejena s tropomiozinsko prevleko iz aktinskega filamenta. Druga regija se nahaja </ins>v <ins style="font-weight: bold; text-decoration: none;">bližini skrajnega C. Ta tropomiozin neodvisna pokrovna domena pokriva čisti aktin.</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Kontrola aktinske filamentne dolžine in dinamike je pomembna za gibljivost celic in zgradbe in je delno urejena </ins>z <ins style="font-weight: bold; text-decoration: none;">limitiranimi beljakovinami, ki zavirajo raztezek in depolimerizacijo na hitro in počasi rastočih koncih. </ins></div></td></tr>
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Milan Obradović