https://wiki.fkkt.uni-lj.si/index.php?action=history&feed=atom&title=Tunikamicin
Tunikamicin - Revision history
2026-04-09T04:24:21Z
Revision history for this page on the wiki
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https://wiki.fkkt.uni-lj.si/index.php?title=Tunikamicin&diff=7837&oldid=prev
MDolinar at 11:55, 4 February 2013
2013-02-04T11:55:30Z
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 11:55, 4 February 2013</td>
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<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>'''Tunikamicin''' je mešanica <del style="font-weight: bold; text-decoration: none;">[[homolog]]nih </del>nukleozidnih [[antibiotiki|antibiotikov]], ki <del style="font-weight: bold; text-decoration: none;">usebuje </del>uracil, N-<del style="font-weight: bold; text-decoration: none;">acetil glukozamin</del>, tunikamin in maščobno kislino, pripeto na aminsko skupino. Obstaja vsaj deset homolognih molekul, ki se med sabo razlikujejo v dolžinah verig maščobnih kislin. </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>'''Tunikamicin''' je mešanica <ins style="font-weight: bold; text-decoration: none;">homolognih </ins>nukleozidnih [[antibiotiki|antibiotikov]], ki <ins style="font-weight: bold; text-decoration: none;">usebujejo </ins>uracil, <ins style="font-weight: bold; text-decoration: none;">[[</ins>N-<ins style="font-weight: bold; text-decoration: none;">acetilglukozamin]]</ins>, <ins style="font-weight: bold; text-decoration: none;">[[</ins>tunikamin<ins style="font-weight: bold; text-decoration: none;">]] </ins>in <ins style="font-weight: bold; text-decoration: none;">[[maščobne kisline|</ins>maščobno kislino<ins style="font-weight: bold; text-decoration: none;">]]</ins>, pripeto na aminsko skupino. Obstaja vsaj deset homolognih molekul, ki se med sabo razlikujejo v dolžinah verig maščobnih kislin. </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Kemijska formula molekule tunikamicina [http://upload.wikimedia.org/wikipedia/commons/thumb/3/34/Tunicamycin.svg/744px-Tunicamycin.svg.png (skica molekule)] je C<sub>38</sub>H<sub>62</sub>N<sub>4</sub>O<sub>16</sub> in najpogostejši homologi imajo med 817 in 859 Da.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Kemijska formula molekule tunikamicina [http://upload.wikimedia.org/wikipedia/commons/thumb/3/34/Tunicamycin.svg/744px-Tunicamycin.svg.png (skica molekule)] je C<sub>38</sub>H<sub>62</sub>N<sub>4</sub>O<sub>16</sub> in najpogostejši homologi imajo med 817 in 859 Da.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Je [[inhibitor]]<del style="font-weight: bold; text-decoration: none;">, ki sodeluje pri transferazah </del>N-<del style="font-weight: bold; text-decoration: none;">glukozamina </del>pri bakterijah in <del style="font-weight: bold; text-decoration: none;">evkarjontih</del>. Zavira sintezo N-<del style="font-weight: bold; text-decoration: none;">glukozamidnih </del>intermediatov in [[glikozilacija|glikozilacijo]] novonastalih glikoproteinov, tako da prepreči prenos N-<del style="font-weight: bold; text-decoration: none;">acetilglikozamina </del>1-fosfata na <del style="font-weight: bold; text-decoration: none;">dilikol monofosfat</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Je [[inhibitor]] N-<ins style="font-weight: bold; text-decoration: none;">acetilglukozamin-transferaz </ins>pri bakterijah in <ins style="font-weight: bold; text-decoration: none;">evkariontih</ins>. Zavira sintezo N-<ins style="font-weight: bold; text-decoration: none;">acetilglukozaminskih lipidnih </ins>intermediatov in [[glikozilacija|glikozilacijo]] novonastalih glikoproteinov, tako da prepreči prenos N-<ins style="font-weight: bold; text-decoration: none;">acetilglukozamin-</ins>1-fosfata na <ins style="font-weight: bold; text-decoration: none;">dolihilmonofosfat</ins>. Tunikamicin poveča aktivnost <ins style="font-weight: bold; text-decoration: none;">[[interferon|</ins>interferona<ins style="font-weight: bold; text-decoration: none;">]], </ins>je pa tudi inhibitor <ins style="font-weight: bold; text-decoration: none;">izločanja [[</ins>ceruloplazmin<ins style="font-weight: bold; text-decoration: none;">|ceruloplazmina]]</ins>, <ins style="font-weight: bold; text-decoration: none;">[[</ins>α2-<ins style="font-weight: bold; text-decoration: none;">makroglobulin|α2-makroglobulina]] </ins>in <ins style="font-weight: bold; text-decoration: none;">inhibitorja </ins>α1-proteaze.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Tunikamicin poveča aktivnost interferona je pa tudi inhibitor <del style="font-weight: bold; text-decoration: none;">za </del>ceruloplazmin, α2-<del style="font-weight: bold; text-decoration: none;">macroglobulin </del>in α1-proteaze.</div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Tunikamicin najpogosteje pridobivajo iz bakterij rodu ''Streptomyces'', najpogosteje iz ''Streptomyces clavuligerus'' in ''Streptomyces Iysosuperficus''.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Tunikamicin najpogosteje pridobivajo iz bakterij rodu ''Streptomyces'', najpogosteje iz ''Streptomyces clavuligerus'' in ''Streptomyces Iysosuperficus''.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>Zaenkrat se ga uporablja le za biološko raziskovanje, ne pa tudi za zdravljenje, čeprav so raziskave pokazale, da deluje proti <del style="font-weight: bold; text-decoration: none;">[[bakterija]]m </del>in <del style="font-weight: bold; text-decoration: none;">[[virus]]om</del>. Učinkovito zavira virus vezikularnega stomatitisa in razvoj raka pri otrocih. </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>Zaenkrat se ga uporablja le za biološko raziskovanje, ne pa tudi za zdravljenje, čeprav so raziskave pokazale, da deluje proti <ins style="font-weight: bold; text-decoration: none;">bakterijam </ins>in <ins style="font-weight: bold; text-decoration: none;">virusom</ins>. Učinkovito zavira virus vezikularnega stomatitisa in razvoj raka pri otrocih. </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko je izoliran, je v obliki belega kristalnega praška. Z vodo se ne meša dobro, dobro topen je v metanolu, piridinu in alkalizirani vodi.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko je izoliran, je v obliki belega kristalnega praška. Z vodo se ne meša dobro, dobro topen je v metanolu, piridinu in alkalizirani vodi.</div></td></tr>
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MDolinar
https://wiki.fkkt.uni-lj.si/index.php?title=Tunikamicin&diff=7678&oldid=prev
Lanaregent at 12:41, 6 January 2013
2013-01-06T12:41:35Z
<p></p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
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<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 12:41, 6 January 2013</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l1">Line 1:</td>
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<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Tunikamicin''' je mešanica [[homolog]]nih nukleozidnih [[antibiotiki|antibiotikov]], ki usebuje uracil, N-acetil glukozamin, tunikamin in maščobno kislino, pripeto na aminsko skupino. Obstaja vsaj deset homolognih molekul, ki se med sabo razlikujejo v dolžinah verig maščobnih kislin. </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>'''Tunikamicin''' je mešanica [[homolog]]nih nukleozidnih [[antibiotiki|antibiotikov]], ki usebuje uracil, N-acetil glukozamin, tunikamin in maščobno kislino, pripeto na aminsko skupino. Obstaja vsaj deset homolognih molekul, ki se med sabo razlikujejo v dolžinah verig maščobnih kislin. </div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Kemijska formula molekule tunikamicina [http://upload.wikimedia.org/wikipedia/commons/thumb/3/34/Tunicamycin.svg/744px-Tunicamycin.svg.png (skica molekule)] je C<sub>38</sub>H<sub>62</sub>N<sub>4</sub>O<sub>16</sub> in najpogostejši homologi imajo med 817 in 859 Da.</ins></div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Je [[inhibitor]], ki sodeluje pri transferazah N-glukozamina pri bakterijah in evkarjontih. Zavira sintezo N-glukozamidnih intermediatov in [[glikozilacija|glikozilacijo]] novonastalih glikoproteinov, tako da prepreči prenos N-acetilglikozamina 1-fosfata na dilikol monofosfat.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Je [[inhibitor]], ki sodeluje pri transferazah N-glukozamina pri bakterijah in evkarjontih. Zavira sintezo N-glukozamidnih intermediatov in [[glikozilacija|glikozilacijo]] novonastalih glikoproteinov, tako da prepreči prenos N-acetilglikozamina 1-fosfata na dilikol monofosfat.</div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Tunikamicin poveča aktivnost interferona je pa tudi inhibitor za ceruloplazmin, α2-macroglobulin in α1-proteaze.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Tunikamicin poveča aktivnost interferona je pa tudi inhibitor za ceruloplazmin, α2-macroglobulin in α1-proteaze.</div></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Tunikamicin najpogosteje pridobivajo iz ''Streptomyces clavuligerus'' in ''Streptomyces Iysosuperficus'', bakterij iz rodu ''Streptomyces''.</del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Zaenkrat se ga uporablja le za biološko raziskovanje, ne pa tudi za zdravljenje, čeprav so raziskave pokazale, da deluje proti [[bakterija]]m in [[virus]]om. Učinkovito zavira virus vezikulatnega stomatitisa in razvoj raka pri otrocih. </del></div></td><td colspan="2" class="diff-side-added"></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">Kemijska formula molekule tunikamicina </del>[<del style="font-weight: bold; text-decoration: none;">http://upload.wikimedia.org/wikipedia/commons/thumb/3/34/Tunicamycin.svg/744px-Tunicamycin.svg.png (skica molekule)</del>] <del style="font-weight: bold; text-decoration: none;">je C<sub>38</sub>H<sub>62</sub>N<sub>4</sub>O<sub>16</sub> </del>in <del style="font-weight: bold; text-decoration: none;">najpogostejši homologi imajo med 817 </del>in <del style="font-weight: bold; text-decoration: none;">859 Da</del>.</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Tunikamicin najpogosteje pridobivajo iz bakterij rodu ''Streptomyces'', najpogosteje iz ''Streptomyces clavuligerus'' in ''Streptomyces Iysosuperficus''.</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">Zaenkrat se ga uporablja le za biološko raziskovanje, ne pa tudi za zdravljenje, čeprav so raziskave pokazale, da deluje proti [</ins>[<ins style="font-weight: bold; text-decoration: none;">bakterija]</ins>]<ins style="font-weight: bold; text-decoration: none;">m </ins>in <ins style="font-weight: bold; text-decoration: none;">[[virus]]om. Učinkovito zavira virus vezikularnega stomatitisa </ins>in <ins style="font-weight: bold; text-decoration: none;">razvoj raka pri otrocih</ins>. </div></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko je izoliran, je v obliki belega kristalnega praška. Z vodo se ne meša dobro, dobro topen je v metanolu, piridinu in alkalizirani vodi.</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>Ko je izoliran, je v obliki belega kristalnega praška. Z vodo se ne meša dobro, dobro topen je v metanolu, piridinu in alkalizirani vodi.</div></td></tr>
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Lanaregent
https://wiki.fkkt.uni-lj.si/index.php?title=Tunikamicin&diff=7677&oldid=prev
Lanaregent: New page: '''Tunikamicin''' je mešanica homolognih nukleozidnih antibiotikov, ki usebuje uracil, N-acetil glukozamin, tunikamin in maščobno kislino, pripeto na aminsko skupino...
2013-01-06T12:33:37Z
<p>New page: '''Tunikamicin''' je mešanica <a href="/index.php?title=Homolog&action=edit&redlink=1" class="new" title="Homolog (page does not exist)">homolognih</a> nukleozidnih <a href="/index.php/Antibiotiki" title="Antibiotiki">antibiotikov</a>, ki usebuje uracil, N-acetil glukozamin, tunikamin in maščobno kislino, pripeto na aminsko skupino...</p>
<p><b>New page</b></p><div>'''Tunikamicin''' je mešanica [[homolog]]nih nukleozidnih [[antibiotiki|antibiotikov]], ki usebuje uracil, N-acetil glukozamin, tunikamin in maščobno kislino, pripeto na aminsko skupino. Obstaja vsaj deset homolognih molekul, ki se med sabo razlikujejo v dolžinah verig maščobnih kislin. <br />
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Je [[inhibitor]], ki sodeluje pri transferazah N-glukozamina pri bakterijah in evkarjontih. Zavira sintezo N-glukozamidnih intermediatov in [[glikozilacija|glikozilacijo]] novonastalih glikoproteinov, tako da prepreči prenos N-acetilglikozamina 1-fosfata na dilikol monofosfat.<br />
Tunikamicin poveča aktivnost interferona je pa tudi inhibitor za ceruloplazmin, α2-macroglobulin in α1-proteaze.<br />
Tunikamicin najpogosteje pridobivajo iz ''Streptomyces clavuligerus'' in ''Streptomyces Iysosuperficus'', bakterij iz rodu ''Streptomyces''.<br />
Zaenkrat se ga uporablja le za biološko raziskovanje, ne pa tudi za zdravljenje, čeprav so raziskave pokazale, da deluje proti [[bakterija]]m in [[virus]]om. Učinkovito zavira virus vezikulatnega stomatitisa in razvoj raka pri otrocih. <br />
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Kemijska formula molekule tunikamicina [http://upload.wikimedia.org/wikipedia/commons/thumb/3/34/Tunicamycin.svg/744px-Tunicamycin.svg.png (skica molekule)] je C<sub>38</sub>H<sub>62</sub>N<sub>4</sub>O<sub>16</sub> in najpogostejši homologi imajo med 817 in 859 Da.<br />
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Ko je izoliran, je v obliki belega kristalnega praška. Z vodo se ne meša dobro, dobro topen je v metanolu, piridinu in alkalizirani vodi.<br />
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== Viri ==<br />
* http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Product_Information_Sheet/1/t7765pis.Par.0001.File.tmp/t7765pis.pdf<br />
* http://www.wikigenes.org/e/chem/e/443603.html#Disease_relevance_of_tunicamycin<br />
* http://www.jbc.org/content/277/38/35289.full<br />
* http://en.wikipedia.org/wiki/Tunicamycin<br />
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[[Category:LEX]]</div>
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